Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | SYNJ2 | O15056 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | ALPL | P05186 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALPI | P09923 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALPG | P10696 | 1/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | GALK1 | P51570 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25243911 | 1.00 | MMP13 (0.44) | MMP13LGALS8EPHX2MAOBSYNJ2 | |
| SCHEMBL30392241 | 0.98 | MMP13 (0.43) | MMP13LGALS8EPHX2MAOBSYNJ2 | |
| SCHEMBL29415360 | 0.98 | MMP13 (0.43) | MMP13LGALS8EPHX2MAOBSYNJ2 | |
| SCHEMBL25417921 | 0.98 | MMP13 (0.43) | MMP13LGALS8EPHX2MAOBSYNJ2 | |
| SCHEMBL30391847 | 0.92 | LGALS8 (0.41) | MMP13LGALS8EPHX2MAOB | |
| SCHEMBL30891356 | 0.92 | LGALS8 (0.41) | MMP13LGALS8EPHX2MAOB | |
| SCHEMBL30391867 | 0.91 | LMNA (0.43) | MMP13LGALS8MAOBSYNJ2MGMT | |
| SCHEMBL20510638 | 0.91 | LGALS8 (0.43) | MMP13LGALS8MAOBSYNJ2KDM4E | |
| SCHEMBL15130853 | 0.91 | MMP13 (0.47) | MMP13LGALS8EPHX2MAOB | |
| SCHEMBL30891291 | 0.90 | MMP13 (0.44) | MMP13LGALS8EPHX2MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3980052-A1 | GLUCOSE-RESPONSIVE INSULIN CONJUGATES | MERCK SHARP & DOHME CORP. (US) | 2022-04-13 | — | — | EP | disclosed |