Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 14/20 | 1.00 |
| ▸ | CHIT1 | Q13231 | 13/20 | 1.00 |
| ▸ | CHIA | Q9BZP6 | 11/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21565763 | 0.87 | CHIT1 (0.79) | KCNH2CHIT1CHIA | |
| SCHEMBL18609493 | 0.87 | CHIT1 (0.79) | KCNH2CHIT1CHIA | |
| SCHEMBL18607828 | 0.87 | CHIT1 (0.79) | KCNH2CHIT1CHIA | |
| SCHEMBL18608072 | 0.87 | CHIT1 (0.79) | KCNH2CHIT1CHIA | |
| SCHEMBL18589509 | 0.85 | CHIT1 (1.00) | KCNH2CHIT1CHIA | |
| SCHEMBL18589439 | 0.85 | CHIT1 (1.00) | KCNH2CHIT1CHIA | |
| SCHEMBL18609714 | 0.85 | CHIT1 (1.00) | KCNH2CHIT1CHIA | |
| SCHEMBL20747182 | 0.85 | CHIT1 (1.00) | KCNH2CHIT1CHIA | |
| SCHEMBL18589319 | 0.85 | CHIT1 (1.00) | KCNH2CHIT1CHIA | |
| SCHEMBL18609492 | 0.85 | CHIT1 (1.00) | KCNH2CHIT1CHIA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 178 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260092053-A1 | KHK INHIBITORS | GILEAD SCIENCES INC (US) | 2026-04-02 | — | — | US | disclosed |
| EP-4359402-B1 | IMIDAZOLO INDAZOLE COMPOUNDS AS JAK INHIBITORS | THERAVANCE BIOPHARMA R&D IP LLC (US) | 2026-03-11 | — | — | EP | disclosed |
| EP-4271674-B9 | CARBOXY-BENZIMIDAZOLE GLP-1R MODULATING COMPOUNDS | GILEAD SCIENCES INC (US) | 2026-03-11 | — | — | EP | disclosed |
| US-12570642-B2 | GLP-IR modulating compounds | GILEAD SCIENCES, INC. (US) | 2026-03-10 | — | — | US | disclosed |
| EP-4346822-B1 | COMPOUND AND COMPOSITION FOR TREATING NON-ALCOHOLIC STEATOHEPATITIS | GILEAD SCIENCES INC (US) | 2026-02-25 | — | — | EP | disclosed |
| US-12559553-B2 | IL-31 modulators for treating FXR-induced pruritus | GILEAD SCIENCES, INC. (US) | 2026-02-24 | — | — | US | disclosed |
| US-20260042788-A1 | STAT6 COMPOUNDS | GILEAD SCIENCES INC (US) | 2026-02-12 | — | — | US | disclosed |
| EP-4691554-A2 | GLP-1R MODULATING COMPOUNDS | Gilead Sciences, Inc. (US) | 2026-02-11 | — | — | EP | disclosed |
| EP-4680333-A1 | PHENYLPIPERIDINE DERIVATIVES AS INHIBITORS OF GLUTAMINYL-PEPTIDE CYCLOTRANSFERASE AND GLUTAMINYL-PEPTIDE CYCLOTRANSFERASE LIKE PROTEIN | Boehringer Ingelheim International GmbH (DE) | 2026-01-21 | — | — | EP | disclosed |
| EP-4681774-A2 | KHK INHIBITORS | Gilead Sciences, Inc. (US) | 2026-01-21 | — | — | EP | disclosed |
| CN-114929712-A | Thienopyrimidinones as TRPA1 inhibitors | 勃林格殷格翰国际有限公司 | 2022-08-19 | — | — | CN | disclosed |
| CN-110382498-B | Fused imidazole-piperidine JAK inhibitors | 施万生物制药研发IP有限责任公司 | 2022-07-12 | — | — | CN | disclosed |
| CN-114630823-A | GLP-1R modulating compounds | 吉利德科学公司 | 2022-06-14 | — | — | CN | disclosed |
| US-20220177449-A1 | GLP-1R MODULATING COMPOUNDS | GILEAD SCIENCES, INC. | 2022-06-09 | — | — | US | disclosed |
| WO-2022109182-A1 | POLYHETEROCYCLIC GLP-1 R MODULATING COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2022-05-27 | — | — | WO | disclosed |
| CN-114555601-A | Novel tetrazoles | 勃林格殷格翰国际有限公司 | 2022-05-27 | — | — | CN | disclosed |
| WO-2022079091-A1 | TETRAZOLE DERIVATIVES AS TRPA1 INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2022-04-21 | — | — | WO | disclosed |
| WO-2022079092-A1 | TETRAZOLE DERIVATIVES AS TRPA1 INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2022-04-21 | — | — | WO | disclosed |
| US-20220112210-A1 | TETRAZOLE DERIVATIVES AS TRPA1 INHIBITORS | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2022-04-14 | — | — | US | disclosed |
| US-20220112202-A1 | TETRAZOLE DERIVATIVES AS TRPA1 INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2022-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220177449-A1 | GLP-1R MODULATING COMPOUNDS | GLP1R, GIPR, GPR119 | KCNH2 3295/4885CHIT1 3809/4885CHIA 2874/4885 |
| US-20260042788-A1 | STAT6 COMPOUNDS | STAT6, IL6ST, NFATC1 | KCNH2 1375/4885CHIT1 715/4885CHIA 1040/4885 |
| US-12559553-B2 | IL-31 modulators for treating FXR-induced pruritus | NR1H4, NR1H3, NR1H2 | KCNH2 2087/4885CHIT1 4498/4885CHIA 4535/4885 |
| US-20260092053-A1 | KHK INHIBITORS | KHK, SLC5A2, HK1 | KCNH2 399/4885CHIT1 796/4885CHIA 2874/4885 |
| US-20220112202-A1 | TETRAZOLE DERIVATIVES AS TRPA1 INHIBITORS | TRPA1, TRPV1, TRPV5 | KCNH2 452/4885CHIT1 4334/4885CHIA 4665/4885 |
| US-20220112210-A1 | TETRAZOLE DERIVATIVES AS TRPA1 INHIBITORS | TRPA1, TRPV1, TRPV5 | KCNH2 452/4885CHIT1 4334/4885CHIA 4665/4885 |
| US-12570642-B2 | GLP-IR modulating compounds | GLP1R, GIPR, GPR119 | KCNH2 1127/4885CHIT1 3324/4885CHIA 2898/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.