SCHEMBL29455876

SCHEMBL29455876

COC(=O)[C@H](Cc1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cn1)NS(C)(=O)=O

nearest known ligand 0.63

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
SIRT2 Q8IXJ6 15/20 0.63
NMBR P28336 1/20 0.43
POLB P06746 1/20 0.41
CA12 O43570 2/20 0.39
CA7 P43166 2/20 0.39
CA9 Q16790 2/20 0.39
CA14 Q9ULX7 2/20 0.39
CA2 P00918 1/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29455733 0.90 SIRT2 (0.53) SIRT2NMBR
SCHEMBL18715386 0.87 SIRT2 (0.67) SIRT2NMBRMEN1KMT2A
SCHEMBL12626396 0.86 SIRT2 (0.66) SIRT2NMBRMEN1KMT2A
SCHEMBL30063496 0.83 SIRT2 (0.84) SIRT2NMBR
SCHEMBL2470124 0.82 SIRT2 (0.64) SIRT2NMBRMEN1KMT2A
SCHEMBL2470129 0.82 SIRT2 (0.64) SIRT2NMBRMEN1KMT2A
SCHEMBL4246949 0.82 SIRT2 (0.67) SIRT2NMBRMEN1KMT2A
SCHEMBL10026711 0.82 SIRT2 (0.64) SIRT2NMBRMEN1KMT2A
SCHEMBL22356512 0.82 SIRT2 (0.61) SIRT2NMBR
SCHEMBL2000374 0.82 SIRT2 (0.61) SIRT2NMBR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3970796-B1 COMPOSITION FOR PREVENTING OR TREATING NEUROTROPHIC KERATITIS WHICH CONTAINS STABILIZED PACAP PEPTIDE SENJU PHARMA CO (JP) 2025-08-20 EP disclosed
US-12304932-B2 PACAP stabilized peptide SENJU PHARMACEUTICAL CO., LTD. (JP) 2025-05-20 US disclosed
US-20220202905-A1 COMPOSITION FOR PREVENTING OR TREATING NEUROTROPHIC KERATITIS WHICH CONTAINS PACAP PEPTIDE OR STABILIZED PACAP PEPTIDE SENJU PHARMACEUTICAL CO., LTD. (JP) 2022-06-30 US disclosed
EP-3970796-A1 COMPOSITION FOR PREVENTING OR TREATING NEUROTROPHIC KERATITIS WHICH CONTAINS PACAP PEPTIDE OR STABILIZED PACAP PEPTIDE Senju Pharmaceutical Co., Ltd. (JP) 2022-03-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12304932-B2 PACAP stabilized peptide VIP, DNPEP, SCTR SIRT2 2759/4885NMBR 639/4885POLB 4810/4885
US-20220202905-A1 COMPOSITION FOR PREVENTING OR TREATING NEUROTROPHIC KERATITIS WHICH CONTAINS PACAP PEPTIDE OR STABILIZED PACAP PEPTIDE BDNF, NTRK2, NGF SIRT2 2927/4885NMBR 282/4885POLB 4355/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.