SCHEMBL29457591

SCHEMBL29457591

NCC(=O)N[C@@H](CCCN=C(N)N)C(=O)NCC(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC(N)=O)C(=O)N1CCC[C@H]1C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ F2R P25116 2/20 0.48
▸ NMUR2 Q9GZQ4 7/20 0.46
▸ NMUR1 Q9HB89 6/20 0.46
▸ BDKRB2 P30411 1/20 0.44
▸ NTSR1 P30989 1/20 0.44
▸ ITGB3 P05106 1/20 0.43
▸ ITGA2B P08514 1/20 0.43
▸ NPY1R P25929 1/20 0.42
▸ F2 P00734 1/20 0.42
▸ GRB2 P62993 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29364295 0.94 BDKRB2 (0.48) F2RBDKRB2NTSR1ITGB3ITGA2B
SCHEMBL29582550 0.89 BDKRB2 (0.48) F2RNMUR2BDKRB2NTSR1F2
SCHEMBL29462901 0.89 KEAP1 (0.46) NTSR1ITGB3ITGA2BF2GRB2
SCHEMBL29364214 0.89 KEAP1 (0.46) NTSR1ITGB3ITGA2BF2GRB2
SCHEMBL29281779 0.88 NMUR2 (0.45) NMUR2NMUR1
SCHEMBL29281778 0.88 NMUR2 (0.45) NMUR2NMUR1
SCHEMBL28313317 0.85 ACE (0.48) F2RF2
SCHEMBL28313314 0.85 ACE (0.48) F2RF2
SCHEMBL30321462 0.84 F2R (0.48) F2RNMUR2NMUR1BDKRB2NTSR1
SCHEMBL29377971 0.84 F2 (0.55) BDKRB2NTSR1F2GRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014283-A1 ULTRASOUND-SENSITIVE PEPTIDE PARTICLES FOR SPATIALLY RESOLVED MOLECULE DELIVERY AND METHODS OF USING THE SAME PENN STATE RES FOUND (US) 2026-01-15 — — US claimed
WO-2025090926-A1 ULTRASOUND-SENSITIVE PEPTIDE PARTICLES WITH SURFACE-BOUND GENE EDITING TOOLS FOR SPATIALLY RESOLVED MOLECULE DELIVERY THE PENN STATE RESEARCH FOUNDATION (US) 2025-05-01 — — WO claimed
US-20240358640-A1 ULTRASOUND-SENSITIVE PEPTIDE PARTICLES FOR SPATIALLY RESOLVED MOLECULE DELIVERY THE PENN STATE RESEARCH FOUNDATION 2024-10-31 — — US claimed
US-12064514-B2 Ultrasound-sensitive peptide particles for spatially resolved molecule delivery THE PENN STATE RESEARCH FOUNDATION (US) 2024-08-20 — — US claimed
US-20240238383-A1 ANTI-OXIDANT CONTAINING PARTICLES AND METHODS OF USE UNIV OF LOWA RESEARCH FOUNDATION (US) 2024-07-18 — — US claimed
US-20240109979-A1 CELL ATTACHMENT MATERIALS, DEVICES AND USES THEREOF FACELLITATE GMBH (DE) 2024-04-04 — — US claimed
EP-4340894-A1 ANTI-OXIDANT CONTAINING PARTICLES AND METHODS OF USE University Of Iowa Research Foundation (US) 2024-03-27 — — EP claimed
EP-4301788-A1 CELL ATTACHMENT MATERIALS, DEVICES AND USES THEREOF FaCellitate GmbH (DE) 2024-01-10 — — EP claimed
WO-2022246280-A1 ANTI-OXIDANT CONTAINING PARTICLES AND METHODS OF USE UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) 2022-11-24 — — WO claimed
WO-2022184899-A1 CELL ATTACHMENT MATERIALS, DEVICES AND USES THEREOF FACELLITATE GMBH (DE) 2022-09-09 — — WO claimed
EP-4053163-A1 CELL ATTACHMENT MATERIALS, DEVICES AND USES THEREOF FaCellitate GmbH (DE) 2022-09-07 — — EP claimed
US-20260108663-A1 LOW PARTICULATE LUBRICIOUS COATING WITH VINYL PYRROLIDONE AND ACIDIC POLYMER-CONTAINING LAYERS SURMODICS INC (US) 2026-04-23 — — US disclosed
US-12552846-B2 Modified BCL9 mimetic peptides Sapience Therapeutics, Inc. (US) 2026-02-17 — — US disclosed
US-20260014283-A1 ULTRASOUND-SENSITIVE PEPTIDE PARTICLES FOR SPATIALLY RESOLVED MOLECULE DELIVERY AND METHODS OF USING THE SAME PENN STATE RES FOUND (US) 2026-01-15 — — US disclosed
EP-4615869-A1 COMBINATION THERAPY COMPRISING BISPECIFIC ANTIBODIES COMPRISING AN NRP1 BINDING DOMAIN Pinetree Therapeutics, Inc. (US) 2025-09-17 — — EP disclosed
US-20220177603-A1 INTRACELLULAR DELIVERY OF ANTI-KRAS ANTIBODIES FORMULATED INTO NANOCAPSULES UNIVERSIDADE DE SANTIAGO DE COMPOSTELA (ES) 2022-06-09 — — US disclosed
EP-3994160-A1 MODIFIED BCL9 MIMETIC PEPTIDES Sapience Therapeutics, Inc. (US) 2022-05-11 — — EP disclosed
WO-2022026906-A9 LYSOSOMAL TARGETING MOLECULES COMPRISING KNOTTIN PEPTIDES AND RELATED COMPOSITIONS AND METHODS THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2022-04-21 — — WO disclosed
EP-3962491-A1 INTRACELLULAR DELIVERY OF ANTI-KRAS ANTIBODIES FORMULATED INTO NANOCAPSULES Universidade De Santiago De Compostela (ES) 2022-03-09 — — EP disclosed
CN-114144424-A Modified BCL9 mimetics 智慧疗法有限公司 2022-03-04 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12552846-B2 Modified BCL9 mimetic peptides BCL9, BCL9L, BCL2L2 F2R 1459/4885NMUR2 2158/4885NMUR1 2708/4885
US-20260014283-A1 ULTRASOUND-SENSITIVE PEPTIDE PARTICLES FOR SPATIALLY RESOLVED MOLECULE DELIVERY AND METHODS OF USING THE SAME HDGFL3, HDGF, HM13 F2R 2018/4885NMUR2 2244/4885NMUR1 2130/4885
US-20260108663-A1 LOW PARTICULATE LUBRICIOUS COATING WITH VINYL PYRROLIDONE AND ACIDIC POLYMER-CONTAINING LAYERS VCL, RAD54L, SELP F2R 638/4885NMUR2 3516/4885NMUR1 3473/4885
US-20220177603-A1 INTRACELLULAR DELIVERY OF ANTI-KRAS ANTIBODIES FORMULATED INTO NANOCAPSULES KRAS, NRAS, TP53 F2R 4090/4885NMUR2 4494/4885NMUR1 4421/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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