SCHEMBL29582550

SCHEMBL29582550

NCC(=O)N[C@@H](CCCN=C(N)N)C(=O)NCC(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ BDKRB2 P30411 2/20 0.48
▸ BDKRB1 P46663 1/20 0.44
▸ NTSR1 P30989 1/20 0.44
▸ F2R P25116 1/20 0.43
▸ F2 P00734 2/20 0.43
▸ NMUR2 Q9GZQ4 1/20 0.43
▸ QRFPR Q96P65 1/20 0.43
▸ APLNR P35414 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29364295 0.95 BDKRB2 (0.48) BDKRB2BDKRB1NTSR1F2RF2
SCHEMBL29457591 0.89 F2R (0.48) BDKRB2NTSR1F2RF2NMUR2
SCHEMBL7935083 0.88 RAMP3 (0.46) NMUR2
SCHEMBL10421719 0.88 RAMP3 (0.46) NMUR2
SCHEMBL30321462 0.86 F2R (0.48) BDKRB2NTSR1F2RF2NMUR2
SCHEMBL29367074 0.85 BDKRB2 (0.50) BDKRB2NTSR1F2NMUR2
SCHEMBL29377971 0.85 F2 (0.55) BDKRB2NTSR1F2APLNR
SCHEMBL28923852 0.85 BDKRB2 (0.50) BDKRB2NTSR1F2NMUR2
SCHEMBL29364214 0.84 KEAP1 (0.46) NTSR1F2
SCHEMBL29462901 0.84 KEAP1 (0.46) NTSR1F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11718687-B2 Biomoletron for regulation stem cell differentiation SOGANGN UNIVERSITY RESEARCH FOUNDATION (KR) 2023-08-08 — — US claimed
US-20240342240-A1 ANTI-ANGIOGENIC TREATMENT USING ECHISTATIN WITH A BLOCKING PEPTIDE CALIFORNIA NORTHSTATE COLLEGE OF PHARMACY (US) 2024-10-17 — — US disclosed
EP-3777877-B1 ADMINISTRATION OF AN ANTAGONIST OF ALPHA 5 BETA1 FOR ANTI-ANTIOGENESIS AND CANCER TREATMENT CALIFORNIA NORTHSTATE COLLEGE OF PHARMACY LLC (US) 2024-08-07 — — EP disclosed
US-12053504-B2 Anti-angiogenic treatment using VLO4 with a blocking peptide CALIFORNIA NORTHSTATE COLLEGE OF PHARMACY, LLC (US) 2024-08-06 — — US disclosed
EP-4389216-A2 PEPTIDE COMPOSITIONS AND THERAPEUTIC USES Allegro Pharmaceuticals, LLC (US) 2024-06-26 — — EP disclosed
US-20240051997-A1 SAP AND PEPTIDOMIMETIC COMPOSITIONS FOR REDUCING SYMPTOMS OF INFLAMMATION VIVEX BIOLOGICS GROUP, INC. 2024-02-15 — — US disclosed
US-20230348534-A1 SAP AND PEPTIDOMIMETICS FOR TREATMENT OF EYE DISEASE VIVEX BIOLOGICS GROUP, INC. 2023-11-02 — — US disclosed
WO-2023191209-A1 MICELLE INCLUDING HYDROPHILIC PEPTIDE AND USE THEREOF 주식회사 퓨전바이오텍 2023-10-05 — — WO disclosed
EP-4241285-A1 SYSTEMS AND METHODS FOR EVALUATING GESTATIONAL PROGRESS AND APPLICATIONS THEREOF The Board of Trustees of the Leland Stanford Junior University (US) 2023-09-13 — — EP disclosed
EP-3768296-B1 SAP AND PEPTIDOMIMETICS FOR TREATMENT OF EYE DISEASE ARCH BIOSURGERY INC (US) 2023-09-06 — — EP disclosed
US-11718687-B2 Biomoletron for regulation stem cell differentiation SOGANGN UNIVERSITY RESEARCH FOUNDATION (KR) 2023-08-08 — — US disclosed
US-20220226431-A1 ANTI-ANGIOGENIC TREATMENT USING VLO4 WITH A BLOCKING PEPTIDE CALIFORNIA NORTHSTATE COLLEGE OF PHARMACY (US) 2022-07-21 — — US disclosed
WO-2022099319-A1 SYSTEMS AND METHODS FOR EVALUATING GESTATIONAL PROGRESS AND APPLICATIONS THEREOF THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITYAN (US) 2022-05-12 — — WO disclosed
US-11318184-B2 Anti-angiogenic treatment with a combination of antagonists CALIFORNIA NORTHSTATE COLLEGE OF PHARMACY, LLC (US) 2022-05-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12053504-B2 Anti-angiogenic treatment using VLO4 with a blocking peptide VCAM1, ITGB2, ITGA2 BDKRB2 222/4885BDKRB1 282/4885NTSR1 879/4885
US-20220226431-A1 ANTI-ANGIOGENIC TREATMENT USING VLO4 WITH A BLOCKING PEPTIDE VCAM1, ITGB2, ITGA2 BDKRB2 222/4885BDKRB1 282/4885NTSR1 879/4885
US-20240342240-A1 ANTI-ANGIOGENIC TREATMENT USING ECHISTATIN WITH A BLOCKING PEPTIDE VCAM1, KDR, TEK BDKRB2 132/4885BDKRB1 200/4885NTSR1 456/4885
US-11318184-B2 Anti-angiogenic treatment with a combination of antagonists VCAM1, ITGA2, ITGB2 BDKRB2 229/4885BDKRB1 257/4885NTSR1 870/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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