SCHEMBL2945816

SCHEMBL2945816

CCO[Si](CCc1ccc(-c2ccc(CBr)cc2)cc1)(OCC)OCC

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 3/20 0.33
MAOB P27338 2/20 0.33
TRPA1 O75762 1/20 0.30
ALDH1A1 P00352 1/20 0.30
TSHR P16473 1/20 0.30
RARB P10826 1/20 0.30
CYP4F2 P78329 1/20 0.30
CYP4A11 Q02928 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL927600 0.95 TRPA1 (0.33) TRPA1ALDH1A1TSHRCYP4F2CYP4A11
SCHEMBL167111 0.85 CYP4F2 (0.37) ALDH1A1CYP4F2CYP4A11
SCHEMBL2948946 0.84 ALDH1A1 (0.33) TRPA1ALDH1A1TSHRCYP4F2CYP4A11
SCHEMBL8138514 0.84 KCNH2 (0.42)
SCHEMBL2953700 0.82 MAOB (0.42) HRH3MAOBTRPA1ALDH1A1TSHR
SCHEMBL2952480 0.82 HRH3 (0.35) HRH3TRPA1ALDH1A1TSHRCYP4F2
SCHEMBL2955367 0.81 LMNA (0.33) TRPA1ALDH1A1TSHR
SCHEMBL3427337 0.80 TAAR1 (0.42)
SCHEMBL12458723 0.80 CYP4F2 (0.33) CYP4F2CYP4A11
SCHEMBL3397084 0.78 CYP1A2 (0.43) HRH3ALDH1A1CYP4F2CYP4A11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7759406-B2 Process for producing polysilsesquioxane graft polymer, pressure-sensitive adhesive, and pressure-sensitive adhesive sheet LINTEC CORPORATION (JP) 2010-07-20 US disclosed
US-20080051487-A1 Process for Producing Polysilsesquioxane Graft Polymer, Pressure-Sensitive Adhesive, and Pressure-Sensitive Adhesive Sheet LINTEC CORPORATION (JP) 2008-02-28 US disclosed