SCHEMBL29458475

SCHEMBL29458475

CCn1c(SCC(=O)Nc2cccc(OC)c2)nnc1-c1ccncc1

nearest known ligand 0.81

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 3/20 0.81
▸ LMNA P02545 1/20 0.69
▸ HTT P42858 1/20 0.69
▸ SMN1; SMN2 Q16637 3/20 0.67
▸ MAPK1 P28482 1/20 0.67
▸ L3MBTL1 Q9Y468 1/20 0.67
▸ MAPT P10636 1/20 0.67
▸ ALDH1A1 P00352 5/20 0.65
▸ KDM4E B2RXH2 1/20 0.65
▸ PKM P14618 1/20 0.65
▸ HPGD P15428 1/20 0.65
▸ TDP1 Q9NUW8 1/20 0.65
▸ TP53 P04637 1/20 0.63
▸ HSD17B10 Q99714 1/20 0.61
▸ USP2 O75604 1/20 0.61
▸ MEN1 O00255 1/20 0.61
▸ KMT2A Q03164 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18559277 0.90 TSHR (1.00) TSHRLMNAHTTSMN1; SMN2MAPK1
SCHEMBL17585394 0.88 TSHR (0.65) TSHRLMNAHTTSMN1; SMN2MAPK1
SCHEMBL16180658 0.88 TSHR (0.64) TSHRLMNAHTTSMN1; SMN2MAPK1
SCHEMBL29692270 0.87 LMNA (0.71) TSHRLMNAHTTSMN1; SMN2MAPK1
SCHEMBL13831882 0.86 KMT2A (0.71) TSHRLMNAHTTSMN1; SMN2MAPK1
SCHEMBL15986488 0.82 HTT (1.00) TSHRLMNAHTTSMN1; SMN2MAPT
SCHEMBL13831468 0.81 TSHR (0.70) TSHRLMNASMN1; SMN2MAPK1L3MBTL1
SCHEMBL13832027 0.80 NPSR1 (0.70) TSHRLMNAHTTSMN1; SMN2MAPT
SCHEMBL13830965 0.80 ALDH1A1 (0.71) LMNAHTTSMN1; SMN2L3MBTL1MAPT
SCHEMBL18559141 0.80 SMN1; SMN2 (1.00) TSHRLMNAHTTSMN1; SMN2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4225993-B1 METHODS OF PRODUCING BIODEGRADABLE AND RECYCLABLE BARRIER PAPER LAMINATE PROCTER & GAMBLE (US) 2026-03-25 — — EP disclosed
US-20260069529-A1 TOPICAL COMPOSITIONS OF MICROCOCCUS LUTEUS Q24 AND USE THEREOF BLIS TECH LIMITED (NZ) 2026-03-12 — — US disclosed
EP-4589059-A2 PROCESS FOR MICROSATELLITE INSTABILITY DETECTION Personal Genome Diagnostics, Inc. (US) 2025-07-23 — — EP disclosed
EP-3717520-B1 PROCESS FOR MICROSATELLITE INSTABILITY DETECTION PERSONAL GENOME DIAGNOSTICS INC (US) 2025-04-16 — — EP disclosed
EP-4225663-B1 BIODEGRADABLE AND RECYCLABLE BARRIER PAPER LAMINATE PROCTER & GAMBLE (US) 2024-10-02 — — EP disclosed
US-20240158990-A1 BIODEGRADABLE AND RECYCLABLE BARRIER PAPER LAMINATE PROCTER & GAMBLE (US) 2024-05-16 — — US disclosed
CN-118013521-A Method for assisting in driving automobile to regularly and safely check 公安部交通管理科学研究所 2024-05-10 — — CN disclosed
US-11821142-B2 Methods of producing biodegradable and recyclable barrier paper laminate THE PROCTER & GAMBLE COMPANY (US) 2023-11-21 — — US disclosed
EP-4225663-A1 BIODEGRADABLE AND RECYCLABLE BARRIER PAPER LAMINATE The Procter & Gamble Company (US) 2023-08-16 — — EP disclosed
EP-4225993-A1 METHODS OF PRODUCING BIODEGRADABLE AND RECYCLABLE BARRIER PAPER LAMINATE The Procter & Gamble Company (US) 2023-08-16 — — EP disclosed
US-20230160002-A1 Process for Microsatellite Instability Detection Personal Genome Diagnostics Inc. (US) 2023-05-25 — — US disclosed
CN-116157268-A Biodegradable and recyclable barrier paper laminate 宝洁公司 2023-05-23 — — CN disclosed
CN-116075427-A Method for producing biodegradable and recyclable barrier paper laminates 宝洁公司 2023-05-05 — — CN disclosed
US-11597967-B2 Process for microsatellite instability detection Personal Genome Diagnostics Inc. (US) 2023-03-07 — — US disclosed
WO-2022077008-A1 BIODEGRADABLE AND RECYCLABLE BARRIER PAPER LAMINATE THE PROCTER & GAMBLE COMPANY (US) 2022-04-14 — — WO disclosed
WO-2022077009-A1 METHODS OF PRODUCING BIODEGRADABLE AND RECYCLABLE BARRIER PAPER LAMINATE THE PROCTER & GAMBLE COMPANY (US) 2022-04-14 — — WO disclosed
US-20220112664-A1 METHODS OF PRODUCING BIODEGRADABLE AND RECYCLABLE BARRIER PAPER LAMINATE THE PROCTER & GAMBLE COMPANY 2022-04-14 — — US disclosed
US-20220112663-A1 BIODEGRADABLE AND RECYCLABLE BARRIER PAPER LAMINATE THE PROCTER & GAMBLE COMPANY 2022-04-14 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260069529-A1 TOPICAL COMPOSITIONS OF MICROCOCCUS LUTEUS Q24 AND USE THEREOF LIPA, LPL, LCT TSHR 4447/4885LMNA 301/4885HTT 3897/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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