Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 7/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.57 |
| ▸ | AHR | P35869 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22644321 | 1.00 | MALT1 (0.58) | MALT1KMT2ANR1I2AHRALDH1A1 | |
| Hydrochloric Acid SCHEMBL22633065 | 0.99 | MALT1 (0.57) | MALT1KMT2ANR1I2AHRALDH1A1 | |
| Hydrochloric Acid SCHEMBL30664787 | 0.99 | MALT1 (0.57) | MALT1KMT2ANR1I2AHRALDH1A1 | |
| SCHEMBL21670326 | 0.89 | MGLL (0.52) | MALT1KMT2ANR1I2AHRMEN1 | |
| Trifluoroacetic Acid SCHEMBL28573625 | 0.87 | MALT1 (0.52) | MALT1KMT2ANR1I2AHRALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL30507515 | 0.87 | MALT1 (0.52) | MALT1KMT2ANR1I2AHRALDH1A1 | |
| Hydrochloric Acid SCHEMBL16150007 | 0.86 | ULK1 (0.49) | KMT2AMEN1SMN1; SMN2ALOX15 | |
| SCHEMBL1534438 | 0.84 | NPC1 (0.53) | KMT2A | |
| SCHEMBL16670833 | 0.84 | ROCK2 (0.45) | MALT1KMT2ANR1I2AHRALDH1A1 | |
| SCHEMBL29621820 | 0.84 | ULK1 (0.47) | KMT2AMEN1GAASMN1; SMN2ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3966205-A1 | AMIDE DERIVATIVES USEFUL IN THE TREATMENT OF HBV INFECTION OR HBV-INDUCED DISEASES | Janssen Sciences Ireland Unlimited Company (IE) | 2022-03-16 | — | — | EP | disclosed |