Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3293719 | 0.82 | MAPT (0.47) | MAPTL3MBTL1MAPK1CYP1A2CYP3A4 | |
| SCHEMBL10585660 | 0.80 | TYR (0.35) | — | |
| SCHEMBL254528 | 0.79 | ALDH1A1 (0.56) | MAPTL3MBTL1MAPK1CYP1A2CYP3A4 | |
| SCHEMBL12231908 | 0.78 | MAPT (0.47) | MAPTL3MBTL1MAPK1CYP1A2CYP3A4 | |
| SCHEMBL11695567 | 0.77 | HSD17B10 (0.54) | MAPTL3MBTL1MAPK1CYP1A2CYP3A4 | |
| SCHEMBL7195325 | 0.77 | HSD17B10 (0.54) | MAPTL3MBTL1MAPK1CYP1A2CYP3A4 | |
| SCHEMBL11307671 | 0.76 | ALDH1A1 (0.48) | MAPTL3MBTL1MAPK1CYP1A2CYP3A4 | |
| SCHEMBL1995212 | 0.76 | MAPT (0.53) | MAPTL3MBTL1MAPK1CYP1A2CYP3A4 | |
| SCHEMBL6196115 | 0.76 | MAPT (0.45) | MAPTL3MBTL1MAPK1CYP1A2CYP3A4 | |
| SCHEMBL5565752 | 0.76 | MAPT (0.45) | MAPTL3MBTL1MAPK1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018229261-A1 | COMBINATION MEDICAMENT COMPRISING A PRODRUG AND INHALABLE CATALYST | ETH Zürich (CH) | 2018-12-20 | — | — | WO | claimed |
| EP-2567964-B1 | Monomer compositions for the synthesis of RNA, methods of synthesis, and methods of deprotection | AGILENT TECHNOLOGIES INC (US) | 2015-02-11 | — | — | EP | claimed |
| EP-2567964-A2 | Monomer Compositions for the Synthesis of RNA, Methods of Synthesis, and Methods of Deprotection | Agilent Technologies, Inc. (US) | 2013-03-13 | — | — | EP | claimed |
| US-7759471-B2 | nucleotide monomer used to make protected RNA that has similar stability to the DNA molecule | AGILENT TECHNOLOGIES, INC. (US) | 2010-07-20 | — | — | US | claimed |
| EP-2001896-A2 | MONOMER COMPOSITIONS FOR THE SYNTHESIS OF RNA, METHODS OF SYNTHESIS, AND METHODS OF DEPROTECTION | Agilent Technologies, Inc. (US) | 2008-12-17 | — | — | EP | claimed |
| WO-2007112263-A2 | MONOMER COMPOSITIONS FOR THE SYNTHESIS OF RNA, METHODS OF SYNTHESIS, AND METHODS OF DEPROTECTION | AGILENT TECHNOLOGIES, INC. (US) | 2007-10-04 | — | — | WO | claimed |
| US-20070100138-A1 | Monomer compositions for the synthesis of polynucleotides, methods of synthesis, and methods of deprotection | THE REGENTS OF THE UNIVERSITY OF COLORADO | 2007-05-03 | — | — | US | claimed |
| US-20070100136-A1 | Monomer compositions for the synthesis of RNA, methods of synthesis, and methods of deprotection | AGILENT TECHNOLOGIES, INC. | 2007-05-03 | — | — | US | claimed |
| WO-2018229261-A1 | COMBINATION MEDICAMENT COMPRISING A PRODRUG AND INHALABLE CATALYST | ETH Zürich (CH) | 2018-12-20 | — | — | WO | disclosed |
| EP-2647713-B1 | MODIFIED SINGLE-STRAND POLYNUCLEOTIDE | DAIICHI SANKYO CO LTD (JP) | 2018-02-21 | — | — | EP | disclosed |
| US-8987226-B2 | Modified single-stranded polynucleotides | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2015-03-24 | — | — | US | disclosed |
| EP-2567964-B1 | Monomer compositions for the synthesis of RNA, methods of synthesis, and methods of deprotection | AGILENT TECHNOLOGIES INC (US) | 2015-02-11 | — | — | EP | disclosed |
| EP-2647713-A1 | MODIFIED SINGLE-STRAND POLYNUCLEOTIDE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2013-10-09 | — | — | EP | disclosed |
| US-8552174-B2 | Solutions, methods, and processes for deprotection of polynucleotides | AGILENT TECHNOLOGIES, INC. (US) | 2013-10-08 | — | — | US | disclosed |
| EP-1095947-A1 | NOVEL ANTIBACTERIAL COMPOUNDS | Sankyo Company Limited (JP) | 2001-05-02 | — | — | EP | disclosed |
| US-5547941-A | VIRICIDES; USED IN TREATMENT OF HIV AND AIDS | FARMITALIA CARLO ERBA S.R.L. (IT) | 1996-08-20 | — | — | US | disclosed |
| EP-0541742-A1 | 2',5'-NUCLEOTIDE ANALOGS AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN S.p.A. (IT) | 1993-05-19 | — | — | EP | disclosed |
| WO-1992021691-A1 | 2',5'-NUCLEOTIDE ANALOGS AS ANTIVIRAL AGENTS | FARMITALIA CARLO ERBA S.R.L. (IT) | 1992-12-10 | — | — | WO | disclosed |
| US-4424331-A | Stable, anaerobically-hardening adhesives containing mixed amine oxide/HN-acidic compound initiators | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1984-01-03 | — | — | US | disclosed |
| US-4386194-A | ACRYLIC ESTERS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1983-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070100136-A1 | Monomer compositions for the synthesis of RNA, methods of synthesis, and methods of deprotection | RNGTT, RNMT, NSUN2 | MAPT 2498/4885L3MBTL1 474/4885MAPK1 3561/4885 |
| US-20070100138-A1 | Monomer compositions for the synthesis of polynucleotides, methods of synthesis, and methods of deprotection | POLN, NT5C3B, PCNA | MAPT 2467/4885L3MBTL1 1596/4885MAPK1 3279/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.