Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PNMT | P11086 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29573123 | 0.89 | PNMT (0.38) | NPC1RAB9APNMTHTR7HTR2B | |
| Hydrochloric Acid SCHEMBL30798995 | 0.87 | NPC1 (0.42) | NPC1RAB9APNMTHTR7HTR2B | |
| Hydrochloric Acid SCHEMBL30798780 | 0.86 | NPC1 (0.39) | NPC1RAB9APNMTHTR7HTR2B | |
| Hydrochloric Acid SCHEMBL30798759 | 0.83 | NPC1 (0.37) | NPC1RAB9APNMTHTR7HTR2B | |
| Hydrochloric Acid SCHEMBL29573426 | 0.83 | PNMT (0.35) | NPC1RAB9APNMTHTR7HTR2B | |
| Hydrochloric Acid SCHEMBL29573680 | 0.81 | NPC1 (0.36) | NPC1RAB9APNMTHTR7HTR2B | |
| Hydrochloric Acid SCHEMBL29573273 | 0.80 | PNMT (0.35) | NPC1RAB9APNMTHTR7HTR2B | |
| Hydrochloric Acid SCHEMBL29574195 | 0.80 | PNMT (0.37) | NPC1RAB9APNMTHTR7HTR2B | |
| Hydrochloric Acid SCHEMBL30799007 | 0.78 | NPC1 (0.35) | NPC1RAB9APNMT | |
| Hydrochloric Acid SCHEMBL30798640 | 0.77 | PNMT (0.32) | NPC1RAB9APNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220185923-A1 | CATALYST SYSTEM | BOREALIS AG (AT) | 2022-06-16 | — | — | US | disclosed |
| EP-3953403-A1 | CATALYST SYSTEM | Borealis AG (AT) | 2022-02-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220185923-A1 | CATALYST SYSTEM | CPNE4, INF2, CAD | NPC1 2085/4885RAB9A 4523/4885PNMT 1069/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.