Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.32 |
| ▸ | ANPEP | P15144 | 1/20 | 0.30 |
| ▸ | IL1RN | P18510 | 1/20 | 0.30 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.30 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | DRD4 | P21917 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30798780 | 0.89 | NPC1 (0.39) | PNMTNPC1RAB9AHTR7HTR2B | |
| Hydrochloric Acid SCHEMBL29459424 | 0.86 | NPC1 (0.31) | NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL30798995 | 0.84 | NPC1 (0.42) | PNMTNPC1RAB9AHTR7HTR2B | |
| Hydrochloric Acid SCHEMBL30798640 | 0.83 | PNMT (0.32) | PNMTNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL29573680 | 0.81 | NPC1 (0.36) | PNMTNPC1RAB9AHTR7HTR2B | |
| Hydrochloric Acid SCHEMBL29573123 | 0.81 | PNMT (0.38) | PNMTNPC1RAB9AHTR7HTR2B | |
| Hydrochloric Acid SCHEMBL30798724 | 0.81 | PNMT (0.32) | PNMT | |
| Hydrochloric Acid SCHEMBL29459231 | 0.80 | NPC1 (0.39) | PNMTNPC1RAB9AHTR7HTR2B | |
| Hydrochloric Acid SCHEMBL10320221 | 0.79 | PNMT (0.41) | PNMTNPC1RAB9AHTR7HTR2B | |
| Hydrochloric Acid SCHEMBL8382925 | 0.79 | PNMT (0.32) | PNMTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260103548-A1 | PROCESS FOR PRODUCING POLYPROPYLENE-ETHYLENE RANDOM COPOLYMER RESIN WITH SUSTAINABLE REACTOR OPERABILITY | W. R. GRACE & CO.-CONN. | 2026-04-16 | — | — | US | disclosed |
| US-12528892-B2 | Alkylation of transition metal coordination catalyst complexes | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2026-01-20 | — | — | US | disclosed |
| US-20250235859-A1 | PROCESS FOR PRODUCING A SINGLE SITE CATALYST | W.R. GRACE & CO.-CONN. (US) | 2025-07-24 | — | — | US | disclosed |
| US-20250235842-A1 | GAS-PHASE PROCESS FOR MAKING POLYPROPYLENE RANDOM COPOLYMERS | W.R. GRACE & CO.-CONN (US) | 2025-07-24 | — | — | US | disclosed |
| US-20250205686-A1 | SILICA-SUPPORTED POLYOLEFIN CATALYST SYSTEM | W. R. GRACE & CO.-CONN. | 2025-06-26 | — | — | US | disclosed |
| EP-4493599-A1 | SILICA-SUPPORTED POLYOLEFIN CATALYST SYSTEM | W. R. Grace & Co.-Conn (US) | 2025-01-22 | — | — | EP | disclosed |
| EP-4493600-A1 | PROCESS FOR PRODUCING HEAT TREATED SUPPORTED ALUMINOXANES IN AN ALIPHATIC SOLVENT USING SOLID ALUMINOXANES | W. R. Grace & Co.-Conn (US) | 2025-01-22 | — | — | EP | disclosed |
| CN-119343380-A | Silica supported polyolefin catalyst system | 格雷斯公司 | 2025-01-21 | — | — | CN | disclosed |
| CN-119234002-A | Method for producing heat-treated supported aluminoxanes in aliphatic solvents using solid aluminoxanes | 格雷斯公司 | 2024-12-31 | — | — | CN | disclosed |
| EP-3105261-B9 | PRODUCING POLYETHYLENE PRODUCTS WITH IMPROVED STIFFNESS, TOUGHNESS, AND PROCESSABILITY | UNIVATION TECH LLC (US) | 2024-10-30 | — | — | EP | disclosed |
| EP-4223802-A2 | POLYMERIZATION CATALYST | Univation Technologies, LLC (US) | 2023-08-09 | — | — | EP | disclosed |
| EP-2953985-B1 | PREPARATION OF POLYOLEFIN | UNIVATION TECH LLC (US) | 2023-06-07 | — | — | EP | disclosed |
| US-20230141606-A1 | Alkylation of Transition Metal Coordination Catalyst Complexes | EXXONMOBIL CHEMICAL PATENTS INC (US) | 2023-05-11 | — | — | US | disclosed |
| WO-2023069328-A1 | PROCESS FOR PRODUCING A SINGLE SITE CATALYST | W.R. GRACE & CO.-CONN. (US) | 2023-04-27 | — | — | WO | disclosed |
| WO-2023018671-A1 | PROCESS FOR PRODUCING POLYOLEFIN GRANULAR RESIN WITH INCREASED SETTLED BULK DENSITY | W.R. GRACE & CO.-CONN. (US) | 2023-02-16 | — | — | WO | disclosed |
| EP-3105261-B1 | PRODUCING POLYETHYLENE PRODUCTS WITH IMPROVED STIFFNESS, TOUGHNESS, AND PROCESSABILITY | UNIVATION TECH LLC (US) | 2022-10-12 | — | — | EP | disclosed |
| EP-4039366-A1 | SUPPORTED CATALYST WITH IMPROVED FLOWABILITY | Univation Technologies, LLC (US) | 2022-08-10 | — | — | EP | disclosed |
| EP-3998292-A1 | PRODUCING POLYETHYLENE PRODUCTS WITH IMPROVED STIFFNESS, TOUGHNESS, AND PROCESSABILITY | Univation Technologies, LLC (US) | 2022-05-18 | — | — | EP | disclosed |
| EP-3998293-A1 | PRODUCING POLYETHYLENE PRODUCTS WITH IMPROVED STIFFNESS, TOUGHNESS, AND PROCESSABILITY | Univation Technologies, LLC (US) | 2022-05-18 | — | — | EP | disclosed |
| EP-2938434-B1 | SUPPORTED CATALYST WITH IMPROVED FLOWABILITY | UNIVATION TECH LLC (US) | 2022-05-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12528892-B2 | Alkylation of transition metal coordination catalyst complexes | LEF1, TAF1, FLI1 | PNMT 2099/4885NPC1 2184/4885RAB9A 3840/4885 |
| US-20230141606-A1 | Alkylation of Transition Metal Coordination Catalyst Complexes | AS3MT, AP1M1, AP3M1 | PNMT 1288/4885NPC1 1405/4885RAB9A 917/4885 |
| US-20260103548-A1 | PROCESS FOR PRODUCING POLYPROPYLENE-ETHYLENE RANDOM COPOLYMER RESIN WITH SUSTAINABLE REACTOR OPERABILITY | CCT4, PTGER1, TCP1 | PNMT 1317/4885NPC1 4558/4885RAB9A 4111/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.