Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | RGS12 | O14924 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23706905 | 1.00 | LMNA (0.35) | LMNAGAAKMT2AMAPTAOC3 | |
| SCHEMBL26132956 | 0.89 | LMNA (0.36) | LMNAKMT2AMAPTRXFP1DRD2 | |
| SCHEMBL26464006 | 0.83 | PIK3CB (0.32) | LMNAMAPTAOC3HSD17B10ALDH1A1 | |
| SCHEMBL23706873 | 0.83 | PIK3CB (0.32) | LMNAMAPTAOC3HSD17B10ALDH1A1 | |
| SCHEMBL29459325 | 0.74 | ALDH1A1 (0.40) | LMNAKMT2AMAPTAOC3DRD2 | |
| SCHEMBL23706910 | 0.74 | ALDH1A1 (0.40) | LMNAKMT2AMAPTAOC3DRD2 | |
| SCHEMBL18189623 | 0.73 | RORC (0.51) | POLB | |
| SCHEMBL23706872 | 0.72 | NPC1 (0.33) | LMNAKMT2AMAPTAOC3HSD17B10 | |
| SCHEMBL26462916 | 0.71 | NPC1 (0.36) | LMNAMAPTHSD17B10ALDH1A1RAB9A | |
| SCHEMBL29459319 | 0.69 | CA2 (0.38) | LMNAKMT2AMAPTRXFP1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022059778-A1 | CYCLIC UREA DERIVATIVE | カルナバイオサイエンス株式会社 | 2022-03-24 | — | — | WO | disclosed |