SCHEMBL29461428

SCHEMBL29461428

CC[C@H](C)[C@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)CN)[C@@H](C)O)C(C)C)[C@@H](C)CC)C(=O)O

nearest known ligand 0.62

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ NTSR1 P30989 3/20 0.59
▸ CALCR P30988 4/20 0.59
▸ NPY2R P49146 7/20 0.58
▸ NPY4R P50391 7/20 0.58
▸ NPY5R Q15761 7/20 0.58
▸ NPY1R P25929 5/20 0.58
▸ OPRD1 P41143 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29811064 0.92 CALCR (0.66) CALCRNPY2RNPY4RNPY5RNPY1R
SCHEMBL30277958 0.91 NPY2R (0.62) NTSR1CALCRNPY2RNPY4RNPY5R
SCHEMBL31182911 0.90 CALCR (0.65) CALCRNPY2RNPY4RNPY5RNPY1R
SCHEMBL29679500 0.90 CALCR (0.64) NTSR1CALCRNPY2RNPY4RNPY5R
SCHEMBL30432228 0.89 NPY2R (0.62) NTSR1CALCRNPY2RNPY4RNPY5R
SCHEMBL30567778 0.89 CALCR (0.66) CALCRNPY2RNPY4RNPY5RNPY1R
SCHEMBL30906377 0.89 NPY2R (0.71) CALCRNPY2RNPY4RNPY5RNPY1R
SCHEMBL29479848 0.89 F2 (0.63) NTSR1CALCRNPY2RNPY4RNPY5R
SCHEMBL30906483 0.88 NPY2R (0.63) NTSR1CALCRNPY2RNPY4RNPY5R
SCHEMBL31182783 0.88 CALCR (0.63) CALCRNPY2RNPY4RNPY5RNPY1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12629409-B2 Vaccine GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2026-05-19 — — US disclosed
US-20240226261-A9 VACCINE GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2024-07-11 — — US disclosed
US-20240131136-A1 VACCINE GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2024-04-25 — — US disclosed
US-11844828-B2 Vaccine GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2023-12-19 — — US disclosed
US-20230248816-A9 PROCESS FOR PREPARING A COMPOSITION COMPRISING A PROTEIN D POLYPEPTIDE GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2023-08-10 — — US disclosed
US-20230066762-A1 IMMUNOGENIC COMPOSITION GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2023-03-02 — — US disclosed
US-20220288190-A1 PROCESS FOR PREPARING A COMPOSITION COMPRISING A PROTEIN D POLYPEPTIDE GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2022-09-15 — — US disclosed
US-20220152182-A1 VACCINE GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2022-05-19 — — US disclosed
US-11266731-B2 Vaccine GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2022-03-08 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220288190-A1 PROCESS FOR PREPARING A COMPOSITION COMPRISING A PROTEIN D POLYPEPTIDE CFD, PEPD, SERPINA6 NTSR1 2610/4885CALCR 415/4885NPY2R 2991/4885
US-20230248816-A9 PROCESS FOR PREPARING A COMPOSITION COMPRISING A PROTEIN D POLYPEPTIDE CFD, PEPD, SERPINA6 NTSR1 2610/4885CALCR 415/4885NPY2R 2991/4885
US-12629409-B2 Vaccine MRPL21, STT3B, CD47 NTSR1 2817/4885CALCR 1824/4885NPY2R 658/4885
US-20230066762-A1 IMMUNOGENIC COMPOSITION CXCL10, CCL2, CCL11 NTSR1 1645/4885CALCR 1308/4885NPY2R 3202/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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