SCHEMBL29461568

SCHEMBL29461568

CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](N)C(C)C)[C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(=O)O)[C@@H](C)O

nearest known ligand 0.65

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ VIPR2 P41587 10/20 0.65
▸ VIPR1 P32241 9/20 0.65
▸ TFPI P10646 1/20 0.58
▸ KEAP1 Q14145 1/20 0.56
▸ HRAS P01112 1/20 0.54
▸ KRAS P01116 1/20 0.54
▸ SOS1 Q07889 1/20 0.54
▸ KISS1R Q969F8 2/20 0.54
▸ CCKBR P32239 1/20 0.54
▸ GLP1R P43220 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29694509 0.96 VIPR2 (0.66) VIPR2VIPR1TFPI
SCHEMBL29694508 0.96 VIPR2 (0.66) VIPR2VIPR1TFPIGLP1R
SCHEMBL29694510 0.92 VIPR2 (0.61) VIPR2VIPR1TFPI
SCHEMBL30432804 0.92 VIPR1 (0.70) VIPR2VIPR1TFPIGLP1R
SCHEMBL30176424 0.91 VIPR1 (0.63) VIPR2VIPR1TFPIGLP1R
SCHEMBL30478240 0.90 VIPR2 (0.62) VIPR2VIPR1KEAP1
SCHEMBL30176435 0.90 VIPR1 (0.69) VIPR2VIPR1TFPICCKBRGLP1R
SCHEMBL30929948 0.90 VIPR2 (0.70) VIPR2VIPR1TFPIKEAP1GLP1R
SCHEMBL30929981 0.90 VIPR2 (0.70) VIPR2VIPR1TFPIKEAP1GLP1R
SCHEMBL30567776 0.89 TFPI (0.69) VIPR2VIPR1TFPIGLP1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12629409-B2 Vaccine GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2026-05-19 — — US disclosed
US-20240226261-A9 VACCINE GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2024-07-11 — — US disclosed
US-20240131136-A1 VACCINE GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2024-04-25 — — US disclosed
US-11844828-B2 Vaccine GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2023-12-19 — — US disclosed
US-20230248816-A9 PROCESS FOR PREPARING A COMPOSITION COMPRISING A PROTEIN D POLYPEPTIDE GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2023-08-10 — — US disclosed
US-20230066762-A1 IMMUNOGENIC COMPOSITION GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2023-03-02 — — US disclosed
US-20220288190-A1 PROCESS FOR PREPARING A COMPOSITION COMPRISING A PROTEIN D POLYPEPTIDE GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2022-09-15 — — US disclosed
US-20220152182-A1 VACCINE GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2022-05-19 — — US disclosed
US-11266731-B2 Vaccine GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2022-03-08 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220288190-A1 PROCESS FOR PREPARING A COMPOSITION COMPRISING A PROTEIN D POLYPEPTIDE CFD, PEPD, SERPINA6 VIPR2 860/4885VIPR1 814/4885TFPI 1391/4885
US-20230248816-A9 PROCESS FOR PREPARING A COMPOSITION COMPRISING A PROTEIN D POLYPEPTIDE CFD, PEPD, SERPINA6 VIPR2 860/4885VIPR1 814/4885TFPI 1391/4885
US-12629409-B2 Vaccine MRPL21, STT3B, CD47 VIPR2 3765/4885VIPR1 3836/4885TFPI 2332/4885
US-20230066762-A1 IMMUNOGENIC COMPOSITION CXCL10, CCL2, CCL11 VIPR2 1911/4885VIPR1 1718/4885TFPI 3568/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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