Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | G6PD | P11413 | 1/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.39 |
| ▸ | MIF | P14174 | 1/20 | 0.37 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 7/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.34 |
| ▸ | SCN4A | P35499 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.33 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.33 |
| ▸ | CHUK | O15111 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL693897 | 0.80 | KIF11 (0.38) | G6PDKIF11KDM4E | |
| SCHEMBL693311 | 0.80 | KIF11 (0.41) | G6PDTLR9MIFPTPN5KIF11 | |
| SCHEMBL692802 | 0.80 | CYP2A6 (0.37) | MIFMEN1KMT2AKDM4E | |
| SCHEMBL3525196 | 0.75 | EPHX2 (0.36) | KIF11EPHX2 | |
| SCHEMBL693157 | 0.70 | BCKDK (0.34) | MIFMEN1KMT2AKDM4E | |
| SCHEMBL693968 | 0.70 | KIF11 (0.38) | G6PDTLR9PTPN5KIF11EPHX2 | |
| SCHEMBL695756 | 0.69 | KIF11 (0.40) | KIF11EPHX2 | |
| SCHEMBL146618 | 0.69 | KIF11 (0.37) | G6PDTLR9MIFPTPN5KIF11 | |
| SCHEMBL145722 | 0.69 | KIF11 (0.40) | G6PDTLR9PTPN5KIF11EPHX2 | |
| SCHEMBL693075 | 0.69 | KIF11 (0.35) | G6PDKIF11KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7754754-B2 | Pharmaceutical formulations containing substituted 2 heteroarylaminoacetic acid compounds | GRUENENTHAL GMBH (DE) | 2010-07-13 | — | — | US | disclosed |
| US-20060025473-A1 | Pharmaceutical formulations containing substituted 2 heteroarylaminoacetic acid compounds | GRUENENTHAL GMBH (DE) | 2006-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060025473-A1 | Pharmaceutical formulations containing substituted 2 heteroarylaminoacetic acid compounds | AADAT, DDC, AADAC | G6PD 1173/4885TLR9 4526/4885MIF 3895/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.