Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 4/20 | 0.41 |
| ▸ | TLR9 | Q9NR96 | 3/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.38 |
| ▸ | TTK | P33981 | 1/20 | 0.37 |
| ▸ | TLR4 | O00206 | 1/20 | 0.35 |
| ▸ | IKBKB | O14920 | 1/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.34 |
| ▸ | CDK9 | P50750 | 2/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.34 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2948404 | 0.97 | CARM1 (0.39) | CARM1TLR9TLR8TLR7PIK3CD | |
| SCHEMBL2956342 | 0.81 | PDE4B (0.42) | CARM1CCNT1CDK9 | |
| SCHEMBL2946218 | 0.81 | CHEK1 (0.47) | CARM1TLR9TLR8TLR7CHEK1 | |
| SCHEMBL2946341 | 0.80 | PIK3CD (0.39) | TLR9TLR8TLR7PIK3CDPIK3R1 | |
| SCHEMBL2948407 | 0.77 | PIK3CD (0.40) | TLR9TLR8TLR7PIK3CDPIK3R1 | |
| SCHEMBL2946279 | 0.75 | PDE4B (0.46) | PIK3CDPIK3R1PIK3CAPIK3CBCCNT1 | |
| SCHEMBL2950517 | 0.74 | ADORA2A (0.40) | CARM1CHEK1 | |
| SCHEMBL2952943 | 0.72 | MAP2K7 (0.45) | PIK3CATTKCHEK1 | |
| SCHEMBL2953250 | 0.70 | CARM1 (0.40) | CARM1TLR9TLR8TLR7CHEK1 | |
| SCHEMBL3135141 | 0.69 | TTK (0.65) | PIK3CBTTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010111406-A2 | COMPOUNDS AND THERAPEUTIC USES THEREOF | MYRIAD PHARMACEUTICALS, INC. (US) | 2010-09-30 | — | — | WO | claimed |