Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 6/20 | 0.40 |
| ▸ | PIK3R1 | P27986 | 6/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 6/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 6/20 | 0.40 |
| ▸ | TTK | P33981 | 1/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.37 |
| ▸ | IKBKB | O14920 | 1/20 | 0.36 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | P4HB | P07237 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2946341 | 0.97 | PIK3CD (0.39) | PIK3CDPIK3R1PIK3CAPIK3CBTTK | |
| SCHEMBL2953492 | 0.87 | TTK (0.47) | PIK3CDPIK3R1PIK3CAPIK3CBTTK | |
| SCHEMBL2956345 | 0.83 | PDE4B (0.42) | TTK | |
| SCHEMBL2948404 | 0.80 | CARM1 (0.39) | PIK3CDPIK3R1PIK3CAPIK3CBTTK | |
| SCHEMBL2946224 | 0.79 | CDK1 (0.40) | TLR9TLR7KCNH2 | |
| SCHEMBL2946339 | 0.77 | CARM1 (0.41) | PIK3CDPIK3R1PIK3CAPIK3CBTTK | |
| SCHEMBL2946285 | 0.75 | PDE4B (0.46) | PIK3CDPIK3R1PIK3CAPIK3CBALDH1A1 | |
| SCHEMBL2950527 | 0.74 | ADORA2A (0.42) | — | |
| SCHEMBL2952950 | 0.72 | DHFR (0.43) | PIK3CATTKMEN1KMT2A | |
| SCHEMBL2953119 | 0.70 | TTK (0.43) | TTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010111406-A2 | COMPOUNDS AND THERAPEUTIC USES THEREOF | MYRIAD PHARMACEUTICALS, INC. (US) | 2010-09-30 | — | — | WO | claimed |