Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 7/20 | 0.47 |
| ▸ | CARM1 | Q86X55 | 6/20 | 0.46 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.39 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.37 |
| ▸ | FLT4 | P35916 | 1/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.36 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.36 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2950517 | 0.90 | ADORA2A (0.40) | CHEK1CARM1PDE7APDE7B | |
| SCHEMBL2953250 | 0.87 | CARM1 (0.40) | CHEK1CARM1TLR9TLR8TLR7 | |
| SCHEMBL2956342 | 0.85 | PDE4B (0.42) | CARM1PDE7APDE7B | |
| SCHEMBL2946339 | 0.81 | CARM1 (0.41) | CHEK1CARM1TLR9TLR8TLR7 | |
| SCHEMBL2948404 | 0.79 | CARM1 (0.39) | CARM1TLR9TLR8TLR7 | |
| SCHEMBL2946279 | 0.79 | PDE4B (0.46) | CHEK1PDE7APDE7B | |
| SCHEMBL2947301 | 0.75 | PDE2A (0.48) | — | |
| SCHEMBL2946524 | 0.74 | HRH4 (0.43) | CHEK1 | |
| SCHEMBL2946224 | 0.74 | CDK1 (0.40) | CHEK1TLR9PTK2FLT4TLR7 | |
| SCHEMBL2953442 | 0.73 | HRH4 (0.42) | CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010111406-A2 | COMPOUNDS AND THERAPEUTIC USES THEREOF | MYRIAD PHARMACEUTICALS, INC. (US) | 2010-09-30 | — | — | WO | claimed |