Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28307662 | 0.72 | — | — | |
| SCHEMBL1466657 | 0.69 | — | — | |
| SCHEMBL9577974 | 0.69 | — | — | |
| SCHEMBL18992124 | 0.65 | PKM (0.50) | PKM | |
| SCHEMBL11202904 | 0.64 | — | — | |
| SCHEMBL4214351 | 0.63 | — | — | |
| SCHEMBL15057770 | 0.62 | — | — | |
| SCHEMBL4728461 | 0.61 | TDP1 (0.33) | PKM | |
| SCHEMBL14470773 | 0.61 | — | — | |
| SCHEMBL9782921 | 0.61 | GRM2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114258318-A | Aminopyrimidine amide autophagy inhibitors and methods of use thereof | 德西费拉制药有限责任公司 | 2022-03-29 | — | — | CN | claimed |
| CN-114258318-A | Aminopyrimidine amide autophagy inhibitors and methods of use thereof | 德西费拉制药有限责任公司 | 2022-03-29 | — | — | CN | disclosed |