Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 4/20 | 0.36 |
| ▸ | MPL | P40238 | 2/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | SLC22A12 | Q96S37 | 3/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | CCR4 | P51679 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19968772 | 1.00 | HSD11B1 (0.36) | HSD11B1MPLNOTUML3MBTL1SCN9A | |
| SCHEMBL19928381 | 0.91 | PTPN1 (0.36) | HSD11B1MPLSCN9ASLC22A12RXFP1 | |
| SCHEMBL29464364 | 0.91 | PTPN1 (0.36) | HSD11B1MPLSCN9ASLC22A12RXFP1 | |
| SCHEMBL29464522 | 0.87 | HSD11B1 (0.36) | HSD11B1L3MBTL1ALDH1A1LMNAGLA | |
| SCHEMBL19925060 | 0.87 | HSD11B1 (0.36) | HSD11B1L3MBTL1ALDH1A1LMNAGLA | |
| SCHEMBL19951312 | 0.87 | PKM (0.35) | HSD11B1L3MBTL1ALDH1A1LMNAGLA | |
| SCHEMBL29464517 | 0.87 | PKM (0.35) | HSD11B1L3MBTL1ALDH1A1LMNAGLA | |
| SCHEMBL19928762 | 0.86 | HSD11B1 (0.38) | HSD11B1L3MBTL1SCN9A | |
| SCHEMBL29464516 | 0.86 | HSD11B1 (0.38) | HSD11B1L3MBTL1SCN9A | |
| SCHEMBL19925159 | 0.84 | RORC (0.38) | HSD11B1SCN9ASLC22A12RXFP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109641873-B | N- (pyridin-2-yl) pyridine-sulfonamide derivatives and their use for the treatment of disease | 诺华股份有限公司 | 2022-03-18 | — | — | CN | claimed |
| CN-109641873-B | N- (pyridin-2-yl) pyridine-sulfonamide derivatives and their use for the treatment of disease | 诺华股份有限公司 | 2022-03-18 | — | — | CN | disclosed |