Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 4/20 | 0.50 |
| ▸ | MAOB | P27338 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.49 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.49 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.49 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.49 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19927769 | 1.00 | MAOA (0.50) | MAOAMAOBHSD17B10MAPK14MAPK13 | |
| SCHEMBL16575341 | 0.80 | HSD17B10 (0.47) | MAOAMAOBHSD17B10MAPK14MAPK13 | |
| SCHEMBL19927726 | 0.79 | RAB9A (0.53) | MAOAMAOBHSD17B10SCN9ACYP3A4 | |
| SCHEMBL29464854 | 0.79 | RAB9A (0.53) | MAOAMAOBHSD17B10SCN9ACYP3A4 | |
| SCHEMBL9876887 | 0.79 | HSD17B10 (0.50) | MAOAMAOBHSD17B10MAPK14MAPK13 | |
| SCHEMBL23585274 | 0.79 | HSD17B10 (0.50) | MAOAMAOBHSD17B10SCN9ACYP3A4 | |
| SCHEMBL7826032 | 0.79 | SCN9A (0.51) | MAOAMAOBHSD17B10SCN9ACYP3A4 | |
| SCHEMBL15454013 | 0.79 | LOXL2 (0.46) | MAOAMAOBHSD17B10MAPK14SCN9A | |
| SCHEMBL30016369 | 0.79 | LOXL2 (0.46) | MAOAMAOBHSD17B10MAPK14SCN9A | |
| SCHEMBL7829875 | 0.76 | LOX (0.46) | MAOAMAOBHSD17B10SCN9ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109641873-B | N- (pyridin-2-yl) pyridine-sulfonamide derivatives and their use for the treatment of disease | 诺华股份有限公司 | 2022-03-18 | — | — | CN | disclosed |