SCHEMBL29464992

SCHEMBL29464992

CCOC(=O)N(C(N)=O)c1ccccc1Cl

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CASP1 P29466 1/20 0.40
ALDH1A1 P00352 8/20 0.39
TSHR P16473 2/20 0.39
GRM6 O15303 1/20 0.39
L3MBTL1 Q9Y468 2/20 0.38
HSD17B10 Q99714 2/20 0.38
LMNA P02545 2/20 0.38
POLB P06746 1/20 0.38
CTDSP1 Q9GZU7 1/20 0.38
NLRP3 Q96P20 1/20 0.38
KDM4E B2RXH2 1/20 0.37
MAPK1 P28482 1/20 0.37
GAA P10253 1/20 0.37
KMT2A Q03164 2/20 0.36
HPGD P15428 1/20 0.36
PDE4B Q07343 1/20 0.36
CYP1A2 P05177 2/20 0.36
CYP3A4 P08684 2/20 0.36
CYP2C9 P11712 2/20 0.36
CYP2C19 P33261 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10869589 0.78 ALDH1A1 (0.48) ALDH1A1TSHRL3MBTL1HSD17B10LMNA
SCHEMBL8324045 0.76 TSHR (0.42) ALDH1A1TSHRL3MBTL1HSD17B10LMNA
SCHEMBL2090175 0.76 ALDH1A1 (0.45) CASP1ALDH1A1L3MBTL1HSD17B10LMNA
SCHEMBL11680618 0.75 TSHR (0.41) CASP1ALDH1A1TSHRL3MBTL1HSD17B10
SCHEMBL7184269 0.74 KMT2A (0.38) ALDH1A1LMNAPOLBKDM4EKMT2A
SCHEMBL1309766 0.73 MAOB (0.50) ALDH1A1HSD17B10LMNAKDM4EGAA
SCHEMBL18741247 0.73 CASP1 (0.34) CASP1ALDH1A1TSHRGRM6L3MBTL1
SCHEMBL6256662 0.73 CES2 (0.41) ALDH1A1TSHRHSD17B10LMNAPOLB
SCHEMBL20118230 0.72 TAS1R3 (0.36) ALDH1A1
SCHEMBL7531399 0.72 CA1 (0.50) ALDH1A1TSHRL3MBTL1HSD17B10LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114372897-A Intelligent construction site centralized management method and system 安徽富煌钢构股份有限公司 2022-04-19 CN claimed
CN-117835198-A Apparatus and method for small data usage enablement in 3GPP networks 交互数字专利控股公司 2024-04-05 CN disclosed
CN-115408502-A Cognitive learning in a synchronous conference to generate scripts that simulate live agent actions 国际商业机器公司 2022-11-29 CN disclosed
CN-114762231-A Power switching apparatus and power supply 安柏电子有限公司 2022-07-15 CN disclosed
CN-114372897-A Intelligent construction site centralized management method and system 安徽富煌钢构股份有限公司 2022-04-19 CN disclosed