SCHEMBL29465612

SCHEMBL29465612

CCOC(=O)[C@@H](CCC(=O)C=[N+]=[N-])NC(=O)[C@H](N)CC(C)C

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.39
KMT2A Q03164 2/20 0.38
POLB P06746 1/20 0.38
NOD1 Q9Y239 3/20 0.36
CTSL P07711 3/20 0.34
CTSB P07858 2/20 0.34
CTSS P25774 1/20 0.34
CTSC P53634 1/20 0.34
PPID Q08752 1/20 0.34
CAPN9 O14815 1/20 0.33
LMNA P02545 1/20 0.33
CAPN1 P07384 1/20 0.33
CTSG P08311 1/20 0.33
ANPEP P15144 2/20 0.32
RNPEP Q9H4A4 2/20 0.32
DNPEP Q9ULA0 1/20 0.32
METAP2 P50579 2/20 0.32
METAP1 P53582 2/20 0.32
ERAP2 Q6P179 1/20 0.32
CAD P27708 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18452348 1.00 L3MBTL1 (0.39) L3MBTL1KMT2APOLBNOD1CTSL
SCHEMBL20465429 1.00 L3MBTL1 (0.39) L3MBTL1KMT2APOLBNOD1CTSL
SCHEMBL20465440 0.97 CTSL (0.39) L3MBTL1KMT2APOLBNOD1CTSL
SCHEMBL18452352 0.97 CTSL (0.39) L3MBTL1KMT2APOLBNOD1CTSL
SCHEMBL18451208 0.88 CTSL (0.32) CTSLCTSBCTSSCTSCANPEP
SCHEMBL20465427 0.88 CTSL (0.32) CTSLCTSBCTSSCTSCANPEP
SCHEMBL20468520 0.88 L3MBTL1 (0.39) L3MBTL1KMT2APOLBNOD1CTSL
SCHEMBL20465422 0.88 L3MBTL1 (0.43) L3MBTL1KMT2APOLBNOD1METAP2
SCHEMBL18451341 0.88 L3MBTL1 (0.43) L3MBTL1KMT2APOLBNOD1METAP2
SCHEMBL30919316 0.88 NOD1 (0.38) L3MBTL1KMT2APOLBNOD1CTSL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250177367-A1 COMBINATION THERAPIES FOR MODULATION OF LIPID PRODUCTION OHIO STATE INNOVATION FOUNDATION 2025-06-05 US claimed
WO-2025073968-A1 COMBINATION OF ROGINOLISIB WITH A MALT1-GLS INHIBITOR IONCTURA SA (CH) 2025-04-10 WO claimed
CN-119677539-A Combination therapy for modulating lipid production 俄亥俄州创新基金会 2025-03-21 CN claimed
EP-4489865-A2 COMBINATION THERAPIES FOR MODULATION OF LIPID PRODUCTION Ohio State Innovation Foundation (US) 2025-01-15 EP claimed
WO-2023172669-A9 COMBINATION THERAPIES FOR MODULATION OF LIPID PRODUCTION OHIO STATE INNOVATION FOUNDATION (US) 2024-08-02 WO claimed
WO-2023172669-A2 COMBINATION THERAPIES FOR MODULATION OF LIPID PRODUCTION OHIO STATE INNOVATION FOUNDATION (US) 2023-09-14 WO claimed
CN-116510024-A Composition, preparation method and application thereof 上海复东生物医药有限责任公司 2023-08-01 CN claimed
EP-4709372-A1 SMALL MOLECULE INHIBITORS OF GLUTAMINASE Leal Therapeutics, Inc. (US) 2026-03-18 EP disclosed
EP-4680215-A1 COMPOSITIONS AND METHODS FOR AMELIORATING ADVERSE EFFECTS OF THERAPIES MDX Management LLC (US) 2026-01-21 EP disclosed
EP-4658641-A1 NOVEL COMPOUNDS THAT CAN BE USED AS THERAPEUTIC AGENTS Xeniom GmbH (DE) 2025-12-10 EP disclosed
US-20250177367-A1 COMBINATION THERAPIES FOR MODULATION OF LIPID PRODUCTION OHIO STATE INNOVATION FOUNDATION 2025-06-05 US disclosed
US-20250161287-A1 METHODS, COMPOSITIONS, AND COMBINATIONS FOR PREVENTING OR TREATING CANCER RECURRENCE VUJA DE SCIENCES INC (US) 2025-05-22 US disclosed
CN-119792538-A Novel therapeutic methods for glioblastoma 昆明医科大学第二附属医院 2025-04-11 CN disclosed
CN-116510024-A Composition, preparation method and application thereof 上海复东生物医药有限责任公司 2023-08-01 CN disclosed
WO-2023085771-A1 ANTICANCER COMPOSITION COMPRISING METABOLIC ANTICANCER DRUG 주식회사 노암 2023-05-19 WO disclosed
WO-2023081775-A1 COMBINATION INHIBITORS FOR TREATING FIBROSIS MEMORIAL SLOAN-KETTERING CANCER CENTER (US) 2023-05-11 WO disclosed
WO-2023081832-A1 METHODS FOR PREVENTING AND TREATING ACUTE KIDNEY INJURY THE JOHNS HOPKINS UNIVERSITY (US) 2023-05-11 WO disclosed
WO-2022251370-A1 METHODS OF TREATING RETINAL VASCULOPATHIES UNITY BIOTECHNOLOGY, INC. (US) 2022-12-01 WO disclosed
CN-114805138-A Prodrug of 6-diazo-5-oxo-L-norleucine, preparation method and application thereof 中国科学院长春应用化学研究所 2022-07-29 CN disclosed
WO-2022056461-A1 USE OF LONG NON-CODING RNAS IN MEDULLOBLASTOMA THE JOHNS HOPKINS UNIVERSITY (US) 2022-03-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250177367-A1 COMBINATION THERAPIES FOR MODULATION OF LIPID PRODUCTION ACACB, SREBF2, FASN L3MBTL1 2294/4885KMT2A 1381/4885POLB 3063/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.