Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 2/20 | 0.50 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29738122 | 0.89 | FGFR1 (0.55) | FGFR1PLA2G4ALMNAALDH1A1TBXA2R | |
| SCHEMBL29465809 | 0.85 | MTNR1A (0.47) | FGFR1PLA2G4ALMNASMN1; SMN2ALOX15 | |
| SCHEMBL2936871 | 0.82 | PLA2G4A (0.49) | FGFR1PLA2G4ALMNASMN1; SMN2ALOX15 | |
| SCHEMBL3838757 | 0.79 | FGFR1 (0.56) | FGFR1PLA2G4ALMNAALDH1A1HDAC1 | |
| SCHEMBL30497305 | 0.78 | MTNR1A (0.51) | FGFR1PLA2G4ALMNASMN1; SMN2HTT | |
| SCHEMBL29556127 | 0.78 | MEN1 (0.56) | FGFR1PLA2G4ALMNASMN1; SMN2MAPT | |
| SCHEMBL26672356 | 0.78 | MEN1 (0.56) | FGFR1PLA2G4ALMNASMN1; SMN2MAPT | |
| SCHEMBL29993514 | 0.77 | FGFR1 (0.49) | FGFR1PLA2G4ALMNASMN1; SMN2HTT | |
| SCHEMBL30782239 | 0.77 | KDM2B (0.51) | FGFR1PLA2G4AHDAC1TBXA2RF2 | |
| SCHEMBL31183038 | 0.77 | HCAR3 (0.55) | FGFR1PLA2G4ALMNAALDH1A1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022117051-A1 | MACROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 北京鞍石生物科技有限责任公司 | 2022-06-09 | — | — | WO | disclosed |