Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC37A4 | O43826 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23748216 | 1.00 | SLC37A4 (0.54) | SLC37A4MEN1KMT2AALDH1A1TP53 | |
| SCHEMBL23748199 | 0.87 | MAPT (0.46) | SLC37A4MEN1KMT2AALDH1A1TP53 | |
| SCHEMBL13149144 | 0.72 | SLC37A4 (0.47) | SLC37A4MEN1KMT2AALDH1A1TP53 | |
| SCHEMBL18801309 | 0.71 | CA12 (0.57) | SLC37A4KMT2AALDH1A1TP53CA12 | |
| SCHEMBL21627106 | 0.71 | L3MBTL1 (0.47) | MEN1KMT2AALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL20924693 | 0.71 | FFAR1 (0.44) | MEN1KMT2AALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL9282939 | 0.70 | LMNA (0.46) | MEN1KMT2AALDH1A1CA12CA1 | |
| SCHEMBL15151899 | 0.69 | SLC37A4 (0.37) | SLC37A4MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL7754193 | 0.69 | SLC37A4 (0.39) | SLC37A4MEN1KMT2AALDH1A1TP53 | |
| SCHEMBL7754195 | 0.69 | SLC37A4 (0.39) | SLC37A4MEN1KMT2AALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114057769-A | Macrocyclic pyridazine compound and application thereof | 上海拓界生物医药科技有限公司 | 2022-02-18 | — | — | CN | disclosed |