SCHEMBL7754193

SCHEMBL7754193

CO/C=C(/Oc1ccc(F)c(CSc2ccccc2)c1C(=O)O)C(=O)OC

nearest known ligand 0.39

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SLC37A4 O43826 1/20 0.39
KMT2A Q03164 3/20 0.35
MEN1 O00255 2/20 0.35
ALDH1A1 P00352 4/20 0.33
KDM4E B2RXH2 1/20 0.33
L3MBTL1 Q9Y468 3/20 0.33
LMNA P02545 3/20 0.33
LTB4R Q15722 2/20 0.32
GAA P10253 2/20 0.32
POLB P06746 1/20 0.32
TRPM5 Q9NZQ8 1/20 0.32
NPC1 O15118 2/20 0.32
RAB9A P51151 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
TP53 P04637 1/20 0.32
HTT P42858 1/20 0.32
CYP2C9 P11712 1/20 0.32
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7754195 1.00 SLC37A4 (0.39) SLC37A4KMT2AMEN1ALDH1A1KDM4E
SCHEMBL7755687 0.88 L3MBTL1 (0.34) SLC37A4KMT2AMEN1L3MBTL1
SCHEMBL7755685 0.88 L3MBTL1 (0.34) SLC37A4KMT2AMEN1L3MBTL1
SCHEMBL7753216 0.80 TDP1 (0.36) KMT2AMEN1ALDH1A1L3MBTL1LMNA
SCHEMBL7753212 0.80 TDP1 (0.36) KMT2AMEN1ALDH1A1L3MBTL1LMNA
SCHEMBL7755660 0.80 CYP4F2 (0.32) ALDH1A1POLB
SCHEMBL7755663 0.80 CYP4F2 (0.32) ALDH1A1POLB
SCHEMBL7753156 0.79 ALDH1A1 (0.40) KMT2AMEN1ALDH1A1KDM4EL3MBTL1
SCHEMBL7753146 0.79 ALDH1A1 (0.40) KMT2AMEN1ALDH1A1KDM4EL3MBTL1
SCHEMBL7801868 0.78 FABP4 (0.34) LMNAPOLBRAB9AHTTCYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20010029239-A1 New herbicidal compositions CRAMP MICHAEL COLIN (GB) 2001-10-11 US disclosed
WO-2001047863-A2 NEW HERBICIDAL COMPOSITIONS AVENTIS CROPSCIENCE SA (FR) 2001-07-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010029239-A1 New herbicidal compositions DDT, CYP1B1, CYP4X1 SLC37A4 3916/4885KMT2A 651/4885MEN1 4657/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.