SCHEMBL2946630

SCHEMBL2946630

CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)NCC(=O)N[C@@H](CO)C(=O)O

nearest known ligand 0.40

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ FAP Q12884 4/20 0.40
▸ OPRD1 P41143 4/20 0.39
▸ OPRM1 P35372 3/20 0.39
▸ F2 P00734 1/20 0.39
▸ RAMP1 O60894 1/20 0.38
▸ CALCRL Q16602 1/20 0.38
▸ FDFT1 P37268 1/20 0.37
▸ ELANE P08246 1/20 0.37
▸ NTSR1 P30989 1/20 0.37
▸ TLR2 O60603 1/20 0.36
▸ CASP3 P42574 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30445992 0.90 CASP3 (0.39) FAPOPRD1OPRM1F2RAMP1
SCHEMBL30139062 0.88 F2 (0.43) FAPOPRD1OPRM1F2FDFT1
SCHEMBL29467321 0.87 F2 (0.45) FAPOPRD1F2FDFT1CASP3
SCHEMBL30139020 0.86 FDFT1 (0.42) FAPOPRD1OPRM1F2FDFT1
SCHEMBL29706165 0.84 XIAP (0.46) ELANE
SCHEMBL29706391 0.84 F2 (0.44) OPRD1F2NTSR1
SCHEMBL27677655 0.84 CASP3 (0.49) TLR2CASP3
SCHEMBL2948552 0.84 CASP3 (0.49) TLR2CASP3
SCHEMBL20888357 0.83 REN (0.40) OPRD1RAMP1CALCRLELANENTSR1
SCHEMBL31540548 0.83 CALCRL (0.43) OPRD1F2RAMP1CALCRLELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1741719-B1 Epithelial cell growth promoter PATENT TECHNOLOGY DEV INC (JP) 2015-02-25 — — EP disclosed
US-8304393-B2 Epithelial cell growth promoter PATENT TECHNOLOGY DEVELOPMENT INC. (JP) 2012-11-06 — — US disclosed
US-20100298235-A1 Epithelial cell growth promoter PATENT TECHNOLOGY DEVELOPMENT INC. (JP) 2010-11-25 — — US disclosed
US-7750115-B2 Epithelial cell growth promoter Patent Technology Development, Inc. (JP) 2010-07-06 — — US disclosed
US-20070213276-A1 A water soluble oligopeptide consisting of glycyl-prolyl-isoleucyl-glycyl-serine or glycyl-prolyl-isoleucyl-glycyl-threonine; hair growth-promoting effect, skin regeneration-promoting effect, therapeutic effect on skin ulcer, and therapeutic effect on mucosal injury PATENT TECHNOLOGY DEVELOPMENT INC. (JP) 2007-09-13 — — US disclosed
EP-1741719-A1 EPITHELIAL CELL GROWTH PROMOTER National Institute of Advanced Industrial Science and Technology (JP) 2007-01-10 — — EP disclosed
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