SCHEMBL29466648

SCHEMBL29466648

Cn1c[n+]([C@@H]2O[C@H](COP(=O)(O)OP(=O)(O)OP(=O)([O-])O)[C@@H](O)[C@H]2O)c2nc(N)[nH]c(=O)c21

nearest known ligand 0.74

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
DCPS Q96C86 1/20 0.72
EIF4E P06730 6/20 0.64
NT5C3B Q969T7 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29438538 0.98 DCPS (0.72) DCPSEIF4ENT5C3B
SCHEMBL29390254 0.94 DCPS (0.70) DCPSEIF4ENT5C3B
SCHEMBL31122854 0.92 DCPS (0.70) DCPSEIF4ENT5C3B
SCHEMBL29824509 0.90 DCPS (0.72) DCPSEIF4ENT5C3B
SCHEMBL29689260 0.85 DCPS (0.92) DCPS
SCHEMBL29361534 0.85 DCPS (0.95) DCPSEIF4E
SCHEMBL29448235 0.76 DCPS (0.76) DCPSEIF4E
SCHEMBL2223109 0.75 TGM2 (0.57) DCPS
SCHEMBL4317980 0.72 DCPS (0.66) DCPS
SCHEMBL18769111 0.70 TGM2 (0.59) DCPS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240240181-A1 NEUROPROTECTIVE MOLECULES AND METHODS OF TREATING NEUROLOGICAL DISORDERS AND INDUCING STRESS GRANULES THE BRIGHAM AND WOMEN'S HOSPITAL, INC. 2024-07-18 US disclosed
US-11866754-B2 Trinucleotide mRNA cap analogs MODERNATX, INC. (US) 2024-01-09 US disclosed
EP-4086269-A1 MRNA CAP ANALOGS WITH MODIFIED PHOSPHATE LINKAGE ModernaTX, Inc. (US) 2022-11-09 EP disclosed
US-11439656-B2 Pharmaceutical compounds and uses thereof REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2022-09-13 US disclosed
US-20220151976-A1 TARGETING LASP1, EIF4A1, EIF4B AND CXC4 WITH MODULATORS AND COMBINATIONS THEREOF FOR CANCER THERAPY THE UNIVERSITY OF TOLEDO (US) 2022-05-19 US disclosed
EP-3362461-B1 MRNA CAP ANALOGS WITH MODIFIED PHOSPHATE LINKAGE MODERNATX INC (US) 2022-03-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220151976-A1 TARGETING LASP1, EIF4A1, EIF4B AND CXC4 WITH MODULATORS AND COMBINATIONS THEREOF FOR CANCER THERAPY LASP1, CXCL12, LAS1L DCPS 4361/4885EIF4E 107/4885NT5C3B 4192/4885
US-11439656-B2 Pharmaceutical compounds and uses thereof TP53, CAPNS1, TP53BP1 DCPS 2122/4885EIF4E 218/4885NT5C3B 2733/4885
US-11866754-B2 Trinucleotide mRNA cap analogs RNGTT, RNMT, CPSF7 DCPS 262/4885EIF4E 72/4885NT5C3B 16/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.