SCHEMBL294669

SCHEMBL294669

C=C[Si](OC)(c1ccccc1)c1ccccc1

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
TSHR P16473 1/20 0.33
CA4 P22748 1/20 0.33
ESR1 P03372 1/20 0.31
ESR2 Q92731 1/20 0.31
HDAC8 Q9BY41 1/20 0.30
TRPA1 O75762 1/20 0.30
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL569492 0.81 ALDH1A1 (0.36) ALDH1A1TSHR
SCHEMBL6890056 0.79 ALDH1A1 (0.35) ALDH1A1TSHR
SCHEMBL2600703 0.78 ESR1 (0.33) ALDH1A1TSHRESR1ESR2
SCHEMBL9402723 0.78 LMNA (0.34) ALDH1A1ESR1ESR2
SCHEMBL6562756 0.77 ALDH1A1 (0.33) ALDH1A1TSHRCA4ESR1ESR2
SCHEMBL143426 0.77 ALDH1A1 (0.33) ALDH1A1TSHRCA4ESR1ESR2
SCHEMBL23921616 0.77 ALDH1A1 (0.34) ALDH1A1TSHRCA4ESR1ESR2
SCHEMBL9901171 0.77 ALDH1A1 (0.33) ALDH1A1TSHR
SCHEMBL2231435 0.77 ALDH1A1 (0.33) ALDH1A1TSHR
SCHEMBL2502766 0.77 MAPK1 (0.31) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 121 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110627974-A High-heat-resistance phosphorus-silicon flame retardant, and preparation method and application thereof 铨盛聚碳科技股份有限公司 2019-12-31 CN claimed
WO-2018048297-A1 ORGANOSILOXANE HYBRID COMPOSITION FOR ENCAPSULATION OF LIGHT-EMITTING ELEMENTS PENCHEM TECHNOLOGIES SDN. BHD. (MY) 2018-03-15 WO claimed
EP-2066734-B1 DIORGANOPOLYSILOXANE AND METHOD OF MANUFACTURING THEREOF DOW CORNING TORAY CO LTD (JP) 2012-10-24 EP claimed
EP-2287231-B1 Ulltraviolet transmissive polyhedral silsesquioxane polymers PANASONIC CORP (JP) 2012-06-06 EP claimed
US-20110251357-A1 ULTRAVIOLET TRANSMISSIVE POLYHEDRAL SILSESQUIOXANE POLYMERS PANASONIC ELECTRIC WORKS CO., LTD. 2011-10-13 US claimed
EP-2287231-A2 Ulltraviolet transmissive polyhedral silesquioxane polymers Panasonic Electric Works Co., Ltd. (JP) 2011-02-23 EP claimed
US-20100113730-A1 Diorganopolysiloxane And Method Of Manufacturing Thereof DOW CORNING TORAY COMPANY, LTD. (JP) 2010-05-06 US claimed
EP-2066734-A1 DIORGANOPOLYSILOXANE AND METHOD OF MANUFACTURING THEREOF Dow Corning Toray Co., Ltd. (JP) 2009-06-10 EP claimed
JP-2008523165-A 2008-07-03 JP claimed
WO-2008038516-A1 DIORGANOPOLYSILOXANE AND METHOD OF MANUFACTURING THEREOF DOW CORNING TORAY CO., LTD. (JP) 2008-04-03 WO claimed
EP-1833880-A1 ULTRAVIOLET TRANSMISSIVE POLYHEDRAL SILSESQUIOXANE POLYMERS Matsushita Electric Works, Ltd. (JP) 2007-09-19 EP claimed
WO-2006062219-A1 ULTRAVIOLET TRANSMISSIVE POLYHEDRAL SILSESQUIOXANE POLYMERS MATSUSHITA ELECTRIC WORKS, LTD. (JP) 2006-06-15 WO claimed
US-20060122351-A1 Ultraviolet transmissive polyhedral silsesquioxane polymers PANASONIC ELECTRIC WORKS CO., LTD. (JP) 2006-06-08 US claimed
US-5344905-A Diorganopolysiloxane and method for the preparation thereof DOW CORNING TORAY SILICONE CO., LTD. (JP) 1994-09-06 US claimed
CN-116675819-A Resin particle, connection material, and connection structure 积水化学工业株式会社 2023-09-01 CN disclosed
CN-115181223-B Low-gloss matte auxiliary agent, preparation method thereof and molded body 铨盛聚碳科技股份有限公司 2023-08-29 CN disclosed
CN-110088160-B Resin particle, connection material, and connection structure 积水化学工业株式会社 2023-06-13 CN disclosed
US-4444936-A ADHESIVE AGENTS FOR CROSSLINKABLE RUBBER DEGUSSA AKTIENGESELLSCHAFT (DE) 1984-04-24 US disclosed
US-4408064-A CATALYTIC SULFIDING OF A VINYL SILANE DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) 1983-10-04 US disclosed
US-4384132-A REINFORCEMENT ADDITIVES FOR CROSSLINKABEL RUBBERS DEGUSSA AKTIENGESELLSCHAFT (DE) 1983-05-17 US disclosed