SCHEMBL9901171

SCHEMBL9901171

C=C[Si](O[Si](O[Si](C=C)(c1ccccc1)c1ccccc1)(O[Si](C=C)(c1ccccc1)c1ccccc1)O[Si](C=C)(c1ccccc1)c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL569492 0.91 ALDH1A1 (0.36) ALDH1A1TSHR
SCHEMBL6890056 0.88 ALDH1A1 (0.35) ALDH1A1TSHR
SCHEMBL841999 0.84 ALDH1A1 (0.32) ALDH1A1TSHR
SCHEMBL667354 0.84 ALDH1A1 (0.32) ALDH1A1TSHR
SCHEMBL2600703 0.83 ESR1 (0.33) ALDH1A1TSHR
SCHEMBL3481880 0.83 ALDH1A1 (0.31) ALDH1A1TSHR
SCHEMBL3482271 0.83 ALDH1A1 (0.31) ALDH1A1TSHR
SCHEMBL6910505 0.83 ALDH1A1 (0.31) ALDH1A1TSHR
SCHEMBL1147931 0.81 ESR1 (0.32) ALDH1A1TSHR
SCHEMBL28431893 0.78 ESR1 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2649114-A1 SILOXANE COMPOSITIONS SUITABLE FOR FORMING ENCAPSULANTS Dow Corning Corporation (US) 2013-10-16 EP disclosed
EP-2649113-A1 SILOXANE COMPOSITIONS INCLUDING METAL-OXIDE NANOPARTICLES SUITABLE FOR FORMING ENCAPSULANTS Dow Corning Corporation (US) 2013-10-16 EP disclosed
EP-2649131-A1 SILOXANE COMPOSITIONS INCLUDING TITANIUM DIOXIDE NANOPARTICLES SUITABLE FOR FORMING ENCAPSULANTS Dow Corning Corporation (US) 2013-10-16 EP disclosed
US-20130256741-A1 Siloxane Compositions Suitable For Forming Encapsulants DOW CORNING CORPORATION 2013-10-03 US disclosed
US-20130256742-A1 Siloxane-Compositions Including Metal-Oxide Nanoparticles Suitable For Forming Encapsulants DOW CORNING CORPORATION (US) 2013-10-03 US disclosed
WO-2012078582-A1 SILOXANE COMPOSITIONS INCLUDING METAL-OXIDE NANOPARTICLES SUITABLE FOR FORMING ENCAPSULANTS DOW CORNING CORPORATION (US) 2012-06-14 WO disclosed
WO-2012078617-A1 SILOXANE COMPOSITIONS INCLUDING TITANIUM DIOXIDE NANOPARTICLES SUITABLE FOR FORMING ENCAPSULANTS DOW CORNING CORPORATION (US) 2012-06-14 WO disclosed
WO-2012078594-A1 SILOXANE COMPOSITIONS SUITABLE FOR FORMING ENCAPSULANTS DOW CORNING CORPORATION (US) 2012-06-14 WO disclosed