SCHEMBL29467280

SCHEMBL29467280

NC(=O)c1cccc(S(=O)(=O)N2CCOCC2)n1

nearest known ligand 0.47

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 1/20 0.47
L3MBTL1 Q9Y468 3/20 0.46
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
ATM Q13315 1/20 0.46
TSHR P16473 1/20 0.45
RECQL P46063 1/20 0.45
TDP1 Q9NUW8 1/20 0.43
POLB P06746 3/20 0.43
ALDH1A1 P00352 2/20 0.43
KDM4E B2RXH2 2/20 0.43
NPSR1 Q6W5P4 1/20 0.43
MAPK1 P28482 1/20 0.43
HTT P42858 2/20 0.42
LMNA P02545 1/20 0.42
HSD17B10 Q99714 1/20 0.42
GPR55 Q9Y2T6 1/20 0.42
GAA P10253 1/20 0.42
USP2 O75604 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9735393 0.78 HSD11B1 (0.50) HSD11B1L3MBTL1MEN1KMT2ATSHR
SCHEMBL3466404 0.73 MAPK1 (0.48) L3MBTL1MEN1KMT2ATDP1POLB
SCHEMBL3465738 0.73 PIM1 (0.47) TSHRTDP1ALDH1A1KDM4ELMNA
SCHEMBL2815393 0.73 IRAK4 (0.60) HSD11B1POLBALDH1A1KDM4EHTT
SCHEMBL9724526 0.72 HSD11B1 (0.46) HSD11B1L3MBTL1MEN1KMT2ATSHR
SCHEMBL3465950 0.72 PIM1 (0.42) TSHRTDP1ALDH1A1KDM4ELMNA
SCHEMBL2850336 0.71 GAA (0.74) MEN1KMT2ATSHRRECQLALDH1A1
SCHEMBL4708071 0.71 PKM (0.59) HSD11B1L3MBTL1MEN1KMT2AATM
SCHEMBL1256021 0.71 CNR1 (0.51) L3MBTL1MEN1KMT2AATMTDP1
SCHEMBL29467287 0.71 CNR1 (0.51) L3MBTL1MEN1KMT2AATMTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022051286-A1 N-LINKED GLYCOSYLATION INHIBITORS AND METHODS OF USING SAME YALE UNIVERSITY (US) 2022-03-10 WO disclosed