Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9734635 | 0.85 | SMN1; SMN2 (0.47) | HSD11B1KMT2AMEN1GAAUSP2 | |
| SCHEMBL9735682 | 0.84 | TSHR (0.49) | HSD11B1KMT2AMEN1USP2SMN1; SMN2 | |
| SCHEMBL9734308 | 0.81 | TSHR (0.41) | HSD11B1L3MBTL1TSHRKDM4ELMNA | |
| SCHEMBL29467280 | 0.78 | HSD11B1 (0.47) | HSD11B1L3MBTL1POLBKMT2AMEN1 | |
| SCHEMBL9724526 | 0.76 | HSD11B1 (0.46) | HSD11B1L3MBTL1POLBKMT2AMEN1 | |
| SCHEMBL4708071 | 0.74 | PKM (0.59) | HSD11B1L3MBTL1POLBKMT2AMEN1 | |
| SCHEMBL3466241 | 0.74 | HSD11B1 (0.51) | HSD11B1PKM | |
| SCHEMBL4580127 | 0.73 | PKM (0.76) | POLBKMT2AMEN1GAASMN1; SMN2 | |
| SCHEMBL12753843 | 0.72 | HSD11B1 (0.58) | HSD11B1 | |
| SCHEMBL9736020 | 0.72 | L3MBTL1 (0.49) | HSD11B1L3MBTL1POLBKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5137886-A | Agriculture | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-08-11 | — | — | US | disclosed |
| EP-0433001-A1 | Insecticidal compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-06-19 | — | — | EP | disclosed |