Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28096203 | 0.71 | ALDH1A1 (0.39) | ALDH1A1MAPT | |
| Cyanate SCHEMBL27860114 | 0.69 | ALDH1A1 (0.38) | ALDH1A1MAPT | |
| SCHEMBL13739079 | 0.66 | ALDH1A1 (0.48) | ALDH1A1MAPT | |
| SCHEMBL22129788 | 0.66 | TSHR (0.32) | — | |
| SCHEMBL2222144 | 0.66 | ALDH1A1 (0.41) | ALDH1A1MAPT | |
| SCHEMBL22126285 | 0.62 | ALDH1A1 (0.73) | ALDH1A1MAPT | |
| Toluene SCHEMBL20393936 | 0.62 | TSHR (0.38) | ALDH1A1MAPT | |
| SCHEMBL29907686 | 0.59 | TRPV4 (0.39) | ALDH1A1MAPT | |
| SCHEMBL4531332 | 0.59 | ALDH1A1 (0.39) | ALDH1A1MAPT | |
| SCHEMBL161677 | 0.59 | ALDH1A1 (0.39) | ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7754225-B2 | Method of protecting against staphylococcal infection | GLAXOSMITHKLINE BIOLOGICALS S.A. (BE) | 2010-07-13 | — | — | US | disclosed |
| EP-2046377-A1 | METHOD OF PROTECTING AGAINST STAPHYLOCOCCAL INFECTION | Nabi Biopharmaceuticals, Inc. (US) | 2009-04-15 | — | — | EP | disclosed |
| WO-2008115254-A1 | METHOD OF PROTECTING AGAINST STAPHYLOCOCCAL INFECTION | NABI BIOPHARMACEUTICALS, INC. (US) | 2008-09-25 | — | — | WO | disclosed |
| US-20080019983-A1 | Method of protecting against staphylococcal infection | NABI BIOPHARMACEUTICALS (US) | 2008-01-24 | — | — | US | disclosed |