Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CHKA | P35790 | 9/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL161677 | 1.00 | ALDH1A1 (0.39) | ALDH1A1TSHRALOX15HSD17B10CHKA | |
| Acetonitrile SCHEMBL28221268 | 0.96 | CHKA (0.36) | ALDH1A1TSHRALOX15HSD17B10CHKA | |
| SCHEMBL1063959 | 0.92 | ALDH1A1 (0.46) | ALDH1A1TSHRALOX15HSD17B10CHKA | |
| Hydrochloric Acid SCHEMBL29199774 | 0.90 | ALDH1A1 (0.43) | ALDH1A1TSHRALOX15HSD17B10CHKA | |
| Bromide SCHEMBL384556 | 0.90 | CHKA (0.47) | ALDH1A1TSHRALOX15HSD17B10CHKA | |
| SCHEMBL1185630 | 0.86 | CHKA (0.41) | ALDH1A1TSHRALOX15HSD17B10CHKA | |
| SCHEMBL1193751 | 0.85 | CHKA (0.32) | ALDH1A1TSHRALOX15HSD17B10CHKA | |
| SCHEMBL7995708 | 0.85 | CHKA (0.36) | ALDH1A1TSHRALOX15HSD17B10CHKA | |
| SCHEMBL3630115 | 0.85 | CHKA (0.36) | ALDH1A1TSHRALOX15HSD17B10CHKA | |
| SCHEMBL1185633 | 0.81 | CHKA (0.36) | ALDH1A1TSHRALOX15HSD17B10CHKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1272530-B1 | CLATHRATE COMPLEXES FORMED BY HYALURONIC ACID DERIVATIVES AND USE THEREOF AS PHARMACEUTICALS | FIDIA FARMACEUTICI (IT) | 2006-09-20 | — | — | EP | claimed |
| US-20040076680-A1 | Clathrate complexes formed by hyaluronic acid derivatives and use thereof as pharmaceuticals | SLOVAK ACADEMY OF SCIENCES (SK) | 2004-04-22 | — | — | US | claimed |
| EP-1272530-A1 | CLATHRATE COMPLEXES FORMED BY HYALURONIC ACID DERIVATIVES AND USE THEREOF AS PHARMACEUTICALS | FIDIA FARMACEUTICI S.p.A. (IT) | 2003-01-08 | — | — | EP | claimed |
| WO-2001066601-A1 | CLATHRATE COMPLEXES FORMED BY HYALURONIC ACID DERIVATIVES AND USE THEREOF AS PHARMACEUTICALS | FIDIA FARMACEUTICI S.P.A. (IT) | 2001-09-13 | — | — | WO | claimed |
| US-7563824-B2 | Clathrate complexes formed by hyaluronic acid derivatives and use thereof as pharmaceuticals | Italian Joint Stock Company (IT) | 2009-07-21 | — | — | US | disclosed |
| EP-1272530-B1 | CLATHRATE COMPLEXES FORMED BY HYALURONIC ACID DERIVATIVES AND USE THEREOF AS PHARMACEUTICALS | FIDIA FARMACEUTICI (IT) | 2006-09-20 | — | — | EP | disclosed |
| US-20040076680-A1 | Clathrate complexes formed by hyaluronic acid derivatives and use thereof as pharmaceuticals | SLOVAK ACADEMY OF SCIENCES (SK) | 2004-04-22 | — | — | US | disclosed |
| EP-1272530-A1 | CLATHRATE COMPLEXES FORMED BY HYALURONIC ACID DERIVATIVES AND USE THEREOF AS PHARMACEUTICALS | FIDIA FARMACEUTICI S.p.A. (IT) | 2003-01-08 | — | — | EP | disclosed |
| US-6309859-B1 | Method for removing N-terminal methionine | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-10-30 | — | — | US | disclosed |
| WO-2001066601-A1 | CLATHRATE COMPLEXES FORMED BY HYALURONIC ACID DERIVATIVES AND USE THEREOF AS PHARMACEUTICALS | FIDIA FARMACEUTICI S.P.A. (IT) | 2001-09-13 | — | — | WO | disclosed |
| US-6066470-A | Method for removing N-terminal methionine | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2000-05-23 | — | — | US | disclosed |
| EP-0812856-B1 | Method for removing N-terminal methionine | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1999-09-29 | — | — | EP | disclosed |
| EP-0812856-A1 | Method for removing N-terminal methionine | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-12-17 | — | — | EP | disclosed |