Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRB2 | P62993 | 1/20 | 0.41 |
| ▸ | CAPN1 | P07384 | 3/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.37 |
| ▸ | APLNR | P35414 | 1/20 | 0.37 |
| ▸ | CMA1 | P23946 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.35 |
| ▸ | NAA50 | Q9GZZ1 | 1/20 | 0.35 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30543475 | 0.95 | GRB2 (0.41) | GRB2CAPN1OPRM1OPRD1APLNR | |
| SCHEMBL38651991 | 0.94 | APLNR (0.43) | GRB2OPRM1OPRD1APLNRNTSR1 | |
| SCHEMBL29468889 | 0.93 | GRB2 (0.42) | GRB2CAPN1OPRM1OPRD1APLNR | |
| SCHEMBL30744292 | 0.90 | APLNR (0.42) | GRB2OPRM1OPRD1APLNRCMA1 | |
| SCHEMBL29760938 | 0.90 | GRB2 (0.41) | GRB2CAPN1OPRM1OPRD1APLNR | |
| SCHEMBL30414346 | 0.89 | GRB2 (0.42) | GRB2CAPN1OPRM1OPRD1CMA1 | |
| SCHEMBL29468872 | 0.88 | GRB2 (0.40) | GRB2OPRM1OPRD1APLNRKMT2A | |
| SCHEMBL30543476 | 0.88 | GRB2 (0.44) | GRB2OPRM1OPRD1APLNRNTSR1 | |
| SCHEMBL29691873 | 0.88 | CAPN1 (0.47) | GRB2CAPN1OPRM1OPRD1APLNR | |
| SCHEMBL31501249 | 0.88 | APLNR (0.41) | GRB2CAPN1OPRM1OPRD1APLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4436991-A1 | PROCESS FOR THE PREPARATION OF TIRZEPATIDE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | Sun Pharmaceutical Industries Limited (IN) | 2024-10-02 | — | — | EP | disclosed |
| EP-4204440-A1 | GLP-1/GIP DUAL AGONISTS | Sun Pharmaceutical Industries Limited (IN) | 2023-07-05 | — | — | EP | disclosed |
| WO-2023089594-A1 | PROCESS FOR THE PREPARATION OF TIRZEPATIDE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | SUN PHARMACEUTICAL INDUSTRIES LIMITED (IN) | 2023-05-25 | — | — | WO | disclosed |
| WO-2022079639-A1 | GLP-1/GIP DUAL AGONISTS | SUN PHARMACEUTICAL INDUSTRIES LIMITED (IN) | 2022-04-21 | — | — | WO | disclosed |