SCHEMBL29468889

SCHEMBL29468889

C[C@H](N)C(=O)NCC(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](COC(C)(C)C)C(=O)N[C@@H](COC(C)(C)C)C(=O)NCC(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](COC(C)(C)C)C(=O)O

nearest known ligand 0.42

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ GRB2 P62993 1/20 0.42
▸ OPRM1 P35372 4/20 0.38
▸ OPRD1 P41143 4/20 0.38
▸ CAPN1 P07384 2/20 0.36
▸ CMA1 P23946 3/20 0.36
▸ CALCRL Q16602 2/20 0.36
▸ APLNR P35414 1/20 0.36
▸ XIAP P98170 1/20 0.36
▸ RAMP1 O60894 1/20 0.36
▸ KMT2A Q03164 1/20 0.36
▸ BDKRB2 P30411 1/20 0.35
▸ NAA50 Q9GZZ1 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31501249 0.94 APLNR (0.41) GRB2OPRM1OPRD1CAPN1CALCRL
SCHEMBL29468804 0.93 GRB2 (0.41) GRB2OPRM1OPRD1CAPN1CMA1
SCHEMBL30543476 0.93 GRB2 (0.44) GRB2OPRM1OPRD1APLNRBDKRB2
SCHEMBL29760938 0.92 GRB2 (0.41) GRB2OPRM1OPRD1CAPN1CMA1
SCHEMBL30543475 0.92 GRB2 (0.41) GRB2OPRM1OPRD1CAPN1CMA1
SCHEMBL30422395 0.91 GRB2 (0.44) GRB2APLNR
SCHEMBL29468872 0.91 GRB2 (0.40) GRB2OPRM1OPRD1CALCRLAPLNR
SCHEMBL30414346 0.90 GRB2 (0.42) GRB2OPRM1OPRD1CAPN1CMA1
SCHEMBL30080461 0.88 OPRM1 (0.46) GRB2OPRM1OPRD1CAPN1XIAP
SCHEMBL29468766 0.88 GRB2 (0.42) GRB2OPRM1OPRD1CAPN1CMA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250019410-A1 PROCESS FOR THE PREPARATION OF TIRZEPATIDE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF SUN PHARMACEUTICAL INDUSTRIES LIMITED (IN) 2025-01-16 — — US disclosed
EP-4436991-A1 PROCESS FOR THE PREPARATION OF TIRZEPATIDE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF Sun Pharmaceutical Industries Limited (IN) 2024-10-02 — — EP disclosed
EP-4204440-A1 GLP-1/GIP DUAL AGONISTS Sun Pharmaceutical Industries Limited (IN) 2023-07-05 — — EP disclosed
WO-2023089594-A1 PROCESS FOR THE PREPARATION OF TIRZEPATIDE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF SUN PHARMACEUTICAL INDUSTRIES LIMITED (IN) 2023-05-25 — — WO disclosed
WO-2022079639-A1 GLP-1/GIP DUAL AGONISTS SUN PHARMACEUTICAL INDUSTRIES LIMITED (IN) 2022-04-21 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250019410-A1 PROCESS FOR THE PREPARATION OF TIRZEPATIDE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF SYK, TREH, QDPR GRB2 1049/4885OPRM1 4271/4885OPRD1 1919/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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