SCHEMBL29468872

SCHEMBL29468872

CC[C@H](C)[C@H](N)C(=O)N[C@@H](C)C(=O)NCC(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](COC(C)(C)C)C(=O)N[C@@H](COC(C)(C)C)C(=O)NCC(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](COC(C)(C)C)C(=O)O

nearest known ligand 0.40

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ GRB2 P62993 1/20 0.40
▸ XIAP P98170 1/20 0.39
▸ ANPEP P15144 1/20 0.37
▸ LNPEP Q9UIQ6 1/20 0.37
▸ APLNR P35414 1/20 0.37
▸ GLP1R P43220 1/20 0.36
▸ GCGR P47871 1/20 0.36
▸ GIPR P48546 1/20 0.36
▸ OPRD1 P41143 3/20 0.36
▸ OPRM1 P35372 1/20 0.36
▸ CALCRL Q16602 2/20 0.35
▸ RAMP1 O60894 1/20 0.35
▸ PTPN1 P18031 1/20 0.35
▸ NPY1R P25929 1/20 0.35
▸ NTSR1 P30989 1/20 0.35
▸ KMT2A Q03164 1/20 0.34
▸ POLB P06746 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30422608 0.92 GRB2 (0.42) GRB2APLNRGLP1RGCGRGIPR
SCHEMBL29468889 0.91 GRB2 (0.42) GRB2XIAPAPLNROPRD1OPRM1
SCHEMBL29760938 0.89 GRB2 (0.41) GRB2APLNROPRD1OPRM1CALCRL
SCHEMBL29468804 0.88 GRB2 (0.41) GRB2APLNROPRD1OPRM1CALCRL
SCHEMBL30543475 0.87 GRB2 (0.41) GRB2APLNROPRD1OPRM1PTPN1
SCHEMBL30414346 0.85 GRB2 (0.42) GRB2XIAPOPRD1OPRM1KMT2A
SCHEMBL30892074 0.85 OPRD1 (0.44) APLNRGLP1RGCGRGIPROPRD1
SCHEMBL31501249 0.85 APLNR (0.41) GRB2APLNROPRD1OPRM1CALCRL
SCHEMBL30543476 0.84 GRB2 (0.44) GRB2APLNRGLP1RGCGRGIPR
SCHEMBL29468766 0.83 GRB2 (0.42) GRB2XIAPOPRD1OPRM1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240424063-A1 LONG ACTING GLP-1/GIP DUAL AGONISTS SUN PHARMACEUTICAL IND LTD (IN) 2024-12-26 — — US disclosed
EP-4204440-A1 GLP-1/GIP DUAL AGONISTS Sun Pharmaceutical Industries Limited (IN) 2023-07-05 — — EP disclosed
EP-4146248-A1 LONG ACTING GLP-1/GIP DUAL AGONISTS Sun Pharmaceutical Industries Limited (IN) 2023-03-15 — — EP disclosed
WO-2022079639-A1 GLP-1/GIP DUAL AGONISTS SUN PHARMACEUTICAL INDUSTRIES LIMITED (IN) 2022-04-21 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240424063-A1 LONG ACTING GLP-1/GIP DUAL AGONISTS GLP1R, GIPR, GPR119 GRB2 524/4885XIAP 2144/4885ANPEP 455/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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