SCHEMBL30414346

SCHEMBL30414346

C[C@H](NC(=O)CNC(=O)[C@H](COC(C)(C)C)NC(=O)[C@@H](N)COC(C)(C)C)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](COC(C)(C)C)C(=O)O

nearest known ligand 0.42

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ GRB2 P62993 1/20 0.42
▸ OPRM1 P35372 4/20 0.42
▸ OPRD1 P41143 4/20 0.42
▸ BDKRB2 P30411 1/20 0.38
▸ CMA1 P23946 3/20 0.38
▸ KMT2A Q03164 1/20 0.38
▸ SLC6A2 P23975 1/20 0.38
▸ CAPN1 P07384 2/20 0.37
▸ XIAP P98170 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30647290 0.96 OPRM1 (0.46) GRB2OPRM1OPRD1BDKRB2CMA1
SCHEMBL29468766 0.96 GRB2 (0.42) GRB2OPRM1OPRD1BDKRB2CMA1
SCHEMBL30543480 0.92 GRB2 (0.46) GRB2OPRM1OPRD1BDKRB2
SCHEMBL30543475 0.91 GRB2 (0.41) GRB2OPRM1OPRD1BDKRB2CMA1
SCHEMBL29468889 0.90 GRB2 (0.42) GRB2OPRM1OPRD1BDKRB2CMA1
SCHEMBL29468832 0.90 GRB2 (0.46) GRB2OPRM1OPRD1BDKRB2
SCHEMBL29468804 0.89 GRB2 (0.41) GRB2OPRM1OPRD1CMA1KMT2A
SCHEMBL31337813 0.89 GRB2 (0.44) GRB2OPRM1OPRD1BDKRB2CMA1
SCHEMBL29468867 0.87 GRB2 (0.39) GRB2OPRM1OPRD1CMA1KMT2A
SCHEMBL30455472 0.87 GRB2 (0.39) GRB2OPRM1OPRD1CMA1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4724471-A1 GLP-1/GIP DUAL, GLP-1/GCG DUAL AND GLP-1/GIP/GCG TRIPLE RECEPTOR AGONISTS Sun Pharmaceutical Industries Limited (IN) 2026-04-15 — — EP disclosed
EP-4624486-A1 POLYPEPTIDE HAVING MODIFIED STRUCTURE AND USE THEREOF Guangdong Raynovent Biotech Co., Ltd. (CN) 2025-10-01 — — EP disclosed
US-20240424063-A1 LONG ACTING GLP-1/GIP DUAL AGONISTS SUN PHARMACEUTICAL IND LTD (IN) 2024-12-26 — — US disclosed
WO-2024252366-A1 GLP-1/GIP DUAL, GLP-1/GCG DUAL AND GLP-1/GIP/GCG TRIPLE RECEPTOR AGONISTS SUN PHARMACEUTICAL INDUSTRIES LIMITED (IN) 2024-12-12 — — WO disclosed
EP-4436991-A1 PROCESS FOR THE PREPARATION OF TIRZEPATIDE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF Sun Pharmaceutical Industries Limited (IN) 2024-10-02 — — EP disclosed
US-20230241178-A1 LONG ACTING GLP-1/GIP DUAL AGONISTS SUN PHARMACEUTICAL IND LTD (IN) 2023-08-03 — — US disclosed
WO-2023089594-A1 PROCESS FOR THE PREPARATION OF TIRZEPATIDE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF SUN PHARMACEUTICAL INDUSTRIES LIMITED (IN) 2023-05-25 — — WO disclosed
EP-4146248-A1 LONG ACTING GLP-1/GIP DUAL AGONISTS Sun Pharmaceutical Industries Limited (IN) 2023-03-15 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230241178-A1 LONG ACTING GLP-1/GIP DUAL AGONISTS GLP1R, GIPR, GPR119 GRB2 524/4885OPRM1 1258/4885OPRD1 923/4885
US-20240424063-A1 LONG ACTING GLP-1/GIP DUAL AGONISTS GLP1R, GIPR, GPR119 GRB2 524/4885OPRM1 1258/4885OPRD1 923/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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