Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.48 |
| ▸ | MEN1 | O00255 | 6/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22660238 | 1.00 | KMT2A (0.48) | KMT2AMEN1GFERPOLBALDH1A1 | |
| SCHEMBL27075271 | 0.78 | ALDH1A1 (0.43) | KMT2AMEN1POLBALDH1A1NPSR1 | |
| SCHEMBL22660263 | 0.76 | KMT2A (0.53) | KMT2AMEN1GFERPOLBALDH1A1 | |
| SCHEMBL29469483 | 0.76 | KMT2A (0.53) | KMT2AMEN1GFERPOLBALDH1A1 | |
| SCHEMBL29469505 | 0.76 | TACR1 (0.40) | KMT2AMEN1POLBALDH1A1GAA | |
| SCHEMBL22660327 | 0.76 | TACR1 (0.40) | KMT2AMEN1POLBALDH1A1GAA | |
| SCHEMBL22660771 | 0.75 | ALDH1A1 (0.68) | KMT2AMEN1GFERPOLBALDH1A1 | |
| SCHEMBL4772581 | 0.75 | HPGD (0.42) | KMT2AMEN1ALDH1A1NPSR1SMN1; SMN2 | |
| SCHEMBL27033930 | 0.73 | KMT2A (0.41) | KMT2AMEN1POLBALDH1A1NPSR1 | |
| SCHEMBL388845 | 0.69 | NPSR1 (0.50) | KMT2AMEN1GFERPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114206443-B | Aromatic or heteroaromatic ring derivative and preparation method and application thereof | 浙江海正药业股份有限公司 | 2024-02-09 | — | — | CN | disclosed |
| US-20220227699-A1 | AROMATIC RING OR HETEROAROMATIC RING DERIVATIVES, PREPARATION METHOD THEREFOR AND USE THEREOF | ZHEJIANG HISUN PHARMACEUTICAL CO., LTD. (CN) | 2022-07-21 | — | — | US | disclosed |
| CN-114206443-A | Aromatic ring or heteroaromatic ring derivative and preparation method and application thereof | 浙江海正药业股份有限公司 | 2022-03-18 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220227699-A1 | AROMATIC RING OR HETEROAROMATIC RING DERIVATIVES, PREPARATION METHOD THEREFOR AND USE THEREOF | AGTR2, AGTR1, AVPR2 | KMT2A 2138/4885MEN1 2236/4885GFER 395/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.