Sugi Predict

Sugi Predict / Compounds / Diphenamide

Diphenamide

Diphenamide

SCHEMBL40535

CN(C)C(=O)C(c1ccccc1)c1ccccc1.Nc1ccccc1C(=O)O

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 4/20 0.48
▸ ALDH1A1 P00352 3/20 0.48
▸ ATM Q13315 1/20 0.46
▸ TDP1 Q9NUW8 1/20 0.44
▸ MEN1 O00255 3/20 0.43
▸ KMT2A Q03164 3/20 0.43
▸ CRHBP P24387 1/20 0.43
▸ CRHR2 Q13324 1/20 0.43
▸ MAPT P10636 2/20 0.42
▸ GAA P10253 1/20 0.42
▸ MMP2 P08253 1/20 0.42
▸ HSD17B10 Q99714 2/20 0.41
▸ OPRM1 P35372 1/20 0.41
▸ OPRL1 P41146 1/20 0.41
▸ NPC1 O15118 1/20 0.41
▸ CASP3 P42574 1/20 0.41
▸ RAB9A P51151 1/20 0.41
▸ SENP8 Q96LD8 1/20 0.41
▸ SENP7 Q9BQF6 1/20 0.41
▸ SENP6 Q9GZR1 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diphenamide SCHEMBL11702462 0.83 TACR1 (0.48) KDM4EALDH1A1ATMTDP1MEN1
Diphenamide SCHEMBL9202269 0.83 ALDH1A1 (0.55) KDM4EALDH1A1ATMTDP1MEN1
Diphenamide SCHEMBL39339 0.83 ALDH1A1 (0.55) KDM4EALDH1A1ATMTDP1MEN1
Diphenamide SCHEMBL6910614 0.83 ALDH1A1 (0.55) KDM4EALDH1A1ATMTDP1MEN1
Diphenamide SCHEMBL15619425 0.83 ALDH1A1 (0.58) KDM4EALDH1A1ATMTDP1MEN1
Diphenamide SCHEMBL9786273 0.81 KDM4E (0.50) KDM4EALDH1A1ATMTDP1MEN1
Diphenamide SCHEMBL23924070 0.81 ALDH1A1 (0.53) KDM4EALDH1A1ATMTDP1MEN1
Diphenamide SCHEMBL2051916 0.81 ALDH1A1 (0.53) KDM4EALDH1A1ATMTDP1MEN1
Diphenamide SCHEMBL22345014 0.81 ALDH1A1 (0.53) KDM4EALDH1A1ATMTDP1MEN1
Diphenamide SCHEMBL11211674 0.81 ALDH1A1 (0.53) KDM4EALDH1A1ATMTDP1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 219 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-217910383-U Reaction device of o-formamido benzamide compound 山东友道化学有限公司 2022-11-29 — — CN claimed
CN-217535871-U Apparatus for producing of o formamido benzamide compound 山东友道化学有限公司 2022-10-04 — — CN claimed
CN-113692406-A Process for preparing o-formamido-benzamide compounds and intermediates thereof PI工业有限公司 2021-11-23 — — CN claimed
US-9854802-B2 Use of an anthranilic diamide derivatives with heteroaromatic and heterocyclic substituents in combination with a biological control agent BAYER INTELLECTUAL PROPERTY GMBH (DE) 2018-01-02 — — US claimed
EP-2729462-B1 METHOD FOR MANUFACTURING TETRAZOLE SUBSTITUTED ANTHRANILIC ACID DERIVATIVES BY CONVERTING PYRAZOLE ACIDS WITH ANTHRANILIC ACID ESTERS BAYER IP GMBH (DE) 2017-10-04 — — EP claimed
EP-2793584-B1 USE OF AN ANTHRANILIC DIAMIDE DERIVATIVES WITH HETEROAROMATIC AND HETEROCYCLIC SUBSTITUENTS IN COMBINATION WITH A BIOLOGICAL CONTROL AGENT BAYER IP GMBH (DE) 2017-08-16 — — EP claimed
US-20170156328-A1 USE OF AN ANTHRANILIC DIAMIDE DERIVATIVES WITH HETEROAROMATIC AND HETEROCYCLIC SUBSTITUENTS IN COMBINATION WITH A BIOLOGICALCONTROL AGENT BAYER INTELLECTUAL PROPERTY GMBH 2017-06-08 — — US claimed
US-9609868-B2 Alkoximino-substituted anthranilic acid diamides as pesticides BAYER CROPSCIENCE AG (DE) 2017-04-04 — — US claimed
US-9572342-B2 Use of an anthranilic diamide derivatives with heteroaromatic and heterocyclic substituents in combination with a biologicalcontrol agent BAYER INTELLECTUAL PROPERTY GMBH (DE) 2017-02-21 — — US claimed
US-20160007603-A1 ALKOXIMINO-SUBSTITUTED ANTHRANILIC ACID DIAMIDES AS PESTICIDES BAYER CROPSCIENCE AG (DE) 2016-01-14 — — US claimed
US-20140364458-A1 USE OF AN ANTHRANILIC DIAMIDE DERIVATIVES WITH HETEROAROMATIC AND HETEROCYCLIC SUBSTITUENTS IN COMBINATION WITH A BIOLOGICALCONTROL AGENT BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2014-12-11 — — US claimed
EP-2793584-A1 USE OF AN ANTHRANILIC DIAMIDE DERIVATIVES WITH HETEROAROMATIC AND HETEROCYCLIC SUBSTITUENTS IN COMBINATION WITH A BIOLOGICAL CONTROL AGENT Bayer Intellectual Property GmbH (DE) 2014-10-29 — — EP claimed
CN-104066329-A Combined use of anthranilamide derivatives with heteroaromatic and heterocyclic substituents and biological control agents BAYER IP GMBH 2014-09-24 — — CN claimed
US-20140235865-A1 METHOD FOR PRODUCING TETRAZOLE-SUBSTITUTED ANTHRANILIC ACID DIAMIDE DERIVATIVES BY REACTING PYRAZOLIC ACIDS WITH ANTHRANILIC ACID ESTERS BAYER INTELLECTUAL PROPERTY GMBH (DE) 2014-08-21 — — US claimed
US-20140194623-A1 PROCESS FOR PREPARING TETRAZOLE-SUBSTITUTED ANTHRANILIC ACID DIAMIDE DERIVATIVES BY REACTING BENZOXAZINONES WITH AMINES BAYER INTELLECTUAL PROPERTY GMBH (DE) 2014-07-10 — — US claimed
CN-103764649-A Method for preparing tetrazole-substituted anthranilic acid diamide derivatives by reacting benzoxazinones with amines BAYER IP GMBH 2014-04-30 — — CN claimed
CN-103702992-A Method for producing tetrazole-substituted anthranilic acid diamide derivatives by reacting pyrazolic acid with anthranilic acid ester BAYER IP GMBH 2014-04-02 — — CN claimed
WO-2013092516-A1 USE OF AN ANTHRANILIC DIAMIDE DERIVATIVES WITH HETEROAROMATIC AND HETEROCYCLIC SUBSTITUENTS IN COMBINATION WITH A BIOLOGICAL CONTROL AGENT BAYER INTELLECTUAL PROPERTY GMBH (DE) 2013-06-27 — — WO claimed
EP-2606732-A1 Use of an anthranilic diamide derivatives with heteroaromatic and heterocyclic substituents in combination with a biological control agent Bayer CropScience AG (DE) 2013-06-26 — — EP claimed
US-20090149506-A1 INSECTICIDAL COMPOSITIONS WITH IMPROVED EFFECT BAYER CROPSCIENCE AG (DE) 2009-06-11 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090149506-A1 INSECTICIDAL COMPOSITIONS WITH IMPROVED EFFECT PTEN, PPA1, NAAA KDM4E 1926/4885ALDH1A1 4673/4885ATM 2222/4885
US-20160007603-A1 ALKOXIMINO-SUBSTITUTED ANTHRANILIC ACID DIAMIDES AS PESTICIDES ANTXR2, DDT, DAO KDM4E 1718/4885ALDH1A1 670/4885ATM 1997/4885
US-20140364458-A1 USE OF AN ANTHRANILIC DIAMIDE DERIVATIVES WITH HETEROAROMATIC AND HETEROCYCLIC SUBSTITUENTS IN COMBINATION WITH A BIOLOGICALCONTROL AGENT CYC1, TPD52L2, DBF4 KDM4E 2659/4885ALDH1A1 2726/4885ATM 2419/4885
US-20140194623-A1 PROCESS FOR PREPARING TETRAZOLE-SUBSTITUTED ANTHRANILIC ACID DIAMIDE DERIVATIVES BY REACTING BENZOXAZINONES WITH AMINES DAO, QDPR, DHX15 KDM4E 593/4885ALDH1A1 1030/4885ATM 2361/4885
US-20170156328-A1 USE OF AN ANTHRANILIC DIAMIDE DERIVATIVES WITH HETEROAROMATIC AND HETEROCYCLIC SUBSTITUENTS IN COMBINATION WITH A BIOLOGICALCONTROL AGENT CYC1, TPD52L2, DBF4 KDM4E 2659/4885ALDH1A1 2726/4885ATM 2419/4885
US-20140235865-A1 METHOD FOR PRODUCING TETRAZOLE-SUBSTITUTED ANTHRANILIC ACID DIAMIDE DERIVATIVES BY REACTING PYRAZOLIC ACIDS WITH ANTHRANILIC ACID ESTERS DAO, QPCT, AADAT KDM4E 1968/4885ALDH1A1 969/4885ATM 3018/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.