SCHEMBL29469563

SCHEMBL29469563

Cn1cc(C(=O)Nc2ccccc2OC(F)(F)C(F)F)c(C(F)(F)F)n1

nearest known ligand 0.53

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.53
POLB P06746 1/20 0.53
TSHR P16473 1/20 0.49
MAPK1 P28482 1/20 0.49
ATM Q13315 1/20 0.44
GAA P10253 2/20 0.43
ALDH1A1 P00352 2/20 0.43
STING1 Q86WV6 1/20 0.41
KMT2A Q03164 3/20 0.41
KDM4E B2RXH2 1/20 0.41
MEN1 O00255 1/20 0.41
HSP90AA1 P07900 1/20 0.41
MAPT P10636 1/20 0.41
NCOA1 Q15788 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
NCOA3 Q9Y6Q9 1/20 0.41
DHODH Q02127 2/20 0.41
IRAK4 Q9NWZ3 1/20 0.40
NTRK1 P04629 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL69473 1.00 LMNA (0.53) LMNAPOLBTSHRMAPK1ATM
SCHEMBL29274932 0.94 LMNA (0.47) LMNAPOLBTSHRMAPK1ATM
SCHEMBL302641 0.93 LMNA (0.53) LMNAPOLBTSHRMAPK1ATM
SCHEMBL672497 0.93 LMNA (0.53) LMNAPOLBTSHRMAPK1ATM
SCHEMBL3062126 0.92 TSHR (0.48) LMNAPOLBTSHRMAPK1ATM
SCHEMBL14761433 0.89 TSHR (0.47) LMNAPOLBTSHRMAPK1GAA
SCHEMBL3067877 0.88 ATM (0.59) LMNATSHRMAPK1ATMGAA
SCHEMBL68046 0.87 TSHR (0.49) LMNATSHRMAPK1ATMGAA
SCHEMBL29419112 0.87 TSHR (0.49) LMNATSHRMAPK1ATMGAA
SCHEMBL3672369 0.87 LMNA (0.46) LMNAPOLBTSHRMAPK1STING1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025124407-A1 PYRAZOLE-SUBSTITUTED ARYL SULFIDE COMPOUND AND USE THEREOF 青岛清原化合物有限公司 2025-06-19 WO disclosed
US-20250115599-A1 2-(HET)ARYL-SUBSTITUTED CONDENSED BICYCLIC HETEROCYCLE DERIVATIVES AS PEST CONTROL AGENTS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2025-04-10 US disclosed
EP-3253757-B1 2-(HET)ARYL-SUBSTITUTED CONDENSED BICYCLIC HETEROCYCLE DERIVATIVES AS PESTICIDES BAYER CROPSCIENCE AG (DE) 2025-03-19 EP disclosed
EP-4384013-A1 PROTEIN AGGREGATION INHIBITING COMPOUNDS FOR PLANT DISEASE CONTROL MAX-PLANCK-GESELLSCHAFT ZUR FÖRDERUNG DER WISSENSCHAFTEN E.V. (DE) 2024-06-19 EP disclosed
EP-3601279-B1 TRICYCLIC CARBOXAMIDES AS CONTROL AGENT FOR ARTHROPODS BAYER ANIMAL HEALTH GMBH (DE) 2023-10-18 EP disclosed
WO-2023073115-A1 PROTEIN AGGREGATION INHIBITING COMPOUNDS FOR PLANT DISEASE CONTROL MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2023-05-04 WO disclosed
US-11632958-B2 Use of fungicides for controlling mosaic scab in apples BAYER AKTIENGESELLSCHAFT (DE) 2023-04-25 US disclosed
EP-4061798-A1 SOLVATES OF ABSCISIC ACID AND LIQUID COMPOSITIONS CONTAINING ABSCISIC ACID Clariant International Ltd (CH) 2022-09-28 EP disclosed
WO-2022128955-A1 STORAGE STABLE AQUEOUS SUSPENSION CONCENTRATES BAYER AKTIENGESELLSCHAFT (DE) 2022-06-23 WO disclosed
CN-114466836-A Solvates of abscisic acid and liquid compositions containing abscisic acid 科莱恩国际有限公司 2022-05-10 CN disclosed
CN-109561676-B Use of N-substituted pyrrolidones for promoting penetration of agrochemical active ingredients 科莱恩国际有限公司 2022-04-29 CN disclosed
CN-113243374-B Heterocyclic compounds as pesticides 拜耳农作物科学股份公司 2022-04-26 CN disclosed
CN-114158553-A Novel pesticide preparation and preparation method thereof 南开沧州渤海新区绿色化工研究有限公司 2022-03-11 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11632958-B2 Use of fungicides for controlling mosaic scab in apples SACM1L, PPM1B, PSPH LMNA 3769/4885POLB 408/4885TSHR 4451/4885
US-20250115599-A1 2-(HET)ARYL-SUBSTITUTED CONDENSED BICYCLIC HETEROCYCLE DERIVATIVES AS PEST CONTROL AGENTS CYP8B1, CYP4B1, CYP1B1 LMNA 822/4885POLB 3173/4885TSHR 1362/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.