SCHEMBL302641

SCHEMBL302641

Cn1cc(C(=O)Nc2ccccc2OC(F)(F)C(F)Cl)c(C(F)(F)F)n1

nearest known ligand 0.53

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.53
POLB P06746 2/20 0.53
TSHR P16473 1/20 0.42
MAPK1 P28482 1/20 0.42
ATM Q13315 1/20 0.42
GAA P10253 2/20 0.41
STING1 Q86WV6 1/20 0.40
DHODH Q02127 2/20 0.39
IRAK4 Q9NWZ3 3/20 0.39
NTRK1 P04629 1/20 0.39
KMT2A Q03164 2/20 0.38
MAPT P10636 1/20 0.38
KDM4E B2RXH2 1/20 0.38
MEN1 O00255 1/20 0.38
ALDH1A1 P00352 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL69473 0.93 LMNA (0.53) LMNAPOLBTSHRMAPK1ATM
SCHEMBL29469563 0.93 LMNA (0.53) LMNAPOLBTSHRMAPK1ATM
SCHEMBL672497 0.90 LMNA (0.53) LMNAPOLBTSHRMAPK1ATM
SCHEMBL528778 0.88 TSHR (0.42) LMNAPOLBTSHRMAPK1ATM
SCHEMBL29779370 0.88 TSHR (0.42) LMNAPOLBTSHRMAPK1ATM
SCHEMBL29274932 0.87 LMNA (0.47) LMNAPOLBTSHRMAPK1ATM
SCHEMBL3062126 0.87 TSHR (0.48) LMNAPOLBTSHRMAPK1ATM
SCHEMBL11962977 0.86 TSHR (0.46) LMNAPOLBTSHRMAPK1ATM
SCHEMBL3041666 0.85 TSHR (0.38) LMNAPOLBTSHRMAPK1GAA
SCHEMBL20560041 0.83 LMNA (0.52) LMNAPOLBATMGAASTING1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 138 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2489262-B1 PESTICIDAL MIXTURES COMPRISING AN ANTHRANILAMIDE INSECTICIDE AND A FUNGICIDE BASF SE (DE) 2018-11-14 EP claimed
US-20150080215-A1 TERNARY PESTICIDAL MIXTURES BASF SE (DE) 2015-03-19 US claimed
US-20140179518-A1 Pesticidal Mixtures Comprising Cyanosulfoximine Compounds BASF SE (DE) 2014-06-26 US claimed
US-20130267414-A1 PESTICIDAL MIXTURES BASF SE (DE) 2013-10-10 US claimed
CN-103155949-A Pesticidal mixtures BASF SE 2013-06-19 CN claimed
US-20130137571-A1 Crystalline Modification of Fipronil BASF SE (DE) 2013-05-30 US claimed
EP-2489263-A2 Pesticidal mixtures comprising an anthranilamide insecticide and a fungicide BASF SE (DE) 2012-08-22 EP claimed
EP-2489264-A2 Pesticidal mixtures comprising an anthranilamide insecticide and a carboxamide fungicide BASF SE (DE) 2012-08-22 EP claimed
EP-2489262-A2 Pesticidal mixtures comprising an anthranilamide insecticide and a fungicide BASF SE (DE) 2012-08-22 EP claimed
JP-2012500824-A 2012-01-12 JP claimed
EP-2091330-A2 PESTICIDAL MIXTURES COMPRISING AN ANTHRANILAMIDE INSECTICIDE AND A FUNGICIDE BASF SE (DE) 2009-08-26 EP claimed
WO-2009063075-A2 FUNGICIDAL MIXTURES II BASF SE (DE) 2009-05-22 WO claimed
WO-2009063076-A2 FUNGICIDAL MIXTURES III BASF SE (DE) 2009-05-22 WO claimed
WO-2009063074-A2 FUNGICIDAL MIXTURES I BASF SE (DE) 2009-05-22 WO claimed
WO-2008148859-A2 FUNGICIDAL MIXTURES BASF SE (DE) 2008-12-11 WO claimed
US-20080255107-A1 Fungicidal Mixtures Comprising N-[2-(Haloalk(Enyl)Oxy)Phenyl]Carboxamides BASF SE (DE) 2008-10-16 US claimed
WO-2008095913-A2 PESTICIDAL MIXTURES BASF SE (DE) 2008-08-14 WO claimed
CN-101237773-A Fungicidal N- [ 2- (haloalkoxy) phenyl ] heteroaryl carboxamides BASF AG (DE) 2008-08-06 CN claimed
WO-2008034787-A2 PESTICIDAL MIXTURES COMPRISING AN ANTHRANILAMIDE INSECTICIDE AND A FUNGICIDE BASF SE (DE) 2008-03-27 WO claimed
WO-2008034785-A2 PESTICIDAL MIXTURES COMPRISING AN ANTHRANILAMIDE INSECTICIDE AND A FUNGICIDE BASF SE (DE) 2008-03-27 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130267414-A1 PESTICIDAL MIXTURES AADAC, CTRL, AAAS LMNA 3546/4885POLB 4261/4885TSHR 3382/4885
US-20140179518-A1 Pesticidal Mixtures Comprising Cyanosulfoximine Compounds CPN1, SRM, STS LMNA 3355/4885POLB 3649/4885TSHR 2897/4885
US-20080255107-A1 Fungicidal Mixtures Comprising N-[2-(Haloalk(Enyl)Oxy)Phenyl]Carboxamides CBR3, CBR1, NAT1 LMNA 2193/4885POLB 3504/4885TSHR 2622/4885
US-20130137571-A1 Crystalline Modification of Fipronil FIP1L1, PTMS, FIBP LMNA 2209/4885POLB 4375/4885TSHR 1449/4885
US-20150080215-A1 TERNARY PESTICIDAL MIXTURES AADAC, AS3MT, DDT LMNA 4360/4885POLB 4562/4885TSHR 3267/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.