SCHEMBL69473

SCHEMBL69473

Cn1cc(C(=O)Nc2ccccc2OC(F)(F)C(F)F)c(C(F)(F)F)n1

nearest known ligand 0.53

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.53
POLB P06746 1/20 0.53
TSHR P16473 1/20 0.49
MAPK1 P28482 1/20 0.49
ATM Q13315 1/20 0.44
GAA P10253 2/20 0.43
ALDH1A1 P00352 2/20 0.43
STING1 Q86WV6 1/20 0.41
KMT2A Q03164 3/20 0.41
KDM4E B2RXH2 1/20 0.41
MEN1 O00255 1/20 0.41
HSP90AA1 P07900 1/20 0.41
MAPT P10636 1/20 0.41
NCOA1 Q15788 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
NCOA3 Q9Y6Q9 1/20 0.41
DHODH Q02127 2/20 0.41
IRAK4 Q9NWZ3 1/20 0.40
NTRK1 P04629 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29469563 1.00 LMNA (0.53) LMNAPOLBTSHRMAPK1ATM
SCHEMBL29274932 0.94 LMNA (0.47) LMNAPOLBTSHRMAPK1ATM
SCHEMBL302641 0.93 LMNA (0.53) LMNAPOLBTSHRMAPK1ATM
SCHEMBL672497 0.93 LMNA (0.53) LMNAPOLBTSHRMAPK1ATM
SCHEMBL3062126 0.92 TSHR (0.48) LMNAPOLBTSHRMAPK1ATM
SCHEMBL14761433 0.89 TSHR (0.47) LMNAPOLBTSHRMAPK1GAA
SCHEMBL3067877 0.88 ATM (0.59) LMNATSHRMAPK1ATMGAA
SCHEMBL68046 0.87 TSHR (0.49) LMNATSHRMAPK1ATMGAA
SCHEMBL29419112 0.87 TSHR (0.49) LMNATSHRMAPK1ATMGAA
SCHEMBL3672369 0.87 LMNA (0.46) LMNAPOLBTSHRMAPK1STING1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1242 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108658816-B N-aryl amidine substituted trifluoroethyl sulfide derivatives useful as acaricides and insecticides 拜尔农作物科学股份公司 2023-05-02 CN claimed
EP-3010893-B1 ARYLSULFIDE AND ARYLSULFOXIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES BAYER CROPSCIENCE AG (DE) 2019-10-02 EP claimed
EP-2489262-B1 PESTICIDAL MIXTURES COMPRISING AN ANTHRANILAMIDE INSECTICIDE AND A FUNGICIDE BASF SE (DE) 2018-11-14 EP claimed
EP-3395171-A1 N-ARYLAMIDINE-SUBSTITUTED TRIFLUOROETHYLSULFIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES Bayer CropScience Aktiengesellschaft (DE) 2018-10-31 EP claimed
EP-3010889-B1 ARYLSULFIDE AND ARYLSULFOXIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES BAYER CROPSCIENCE AG (DE) 2018-10-03 EP claimed
EP-2793578-B1 N-ARYLAMIDINE-SUBSTITUTED TRIFLUOROETHYLSULFIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES BAYER CROPSCIENCE AG (DE) 2018-06-06 EP claimed
US-20180103640-A1 PROCESS FOR IMPROVING SEEDLING GROWTH AND/OR EARLY EMERGENCE OF CROPS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2018-04-19 US claimed
US-20170265470-A1 Anthranilamides in combination with fungicides BAYER INTELLECTUAL PROPERTY GMBH (DE) 2017-09-21 US claimed
US-9642363-B2 N-arylamidine-substituted trifluoroethyl sulfide derivatives as acaricides and insecticides BAYER CROPSCIENCE AG (DE) 2017-05-09 US claimed
US-20160278386-A1 COMPOSITIONS COMPRISING A BIOLOGICAL CONTROL AGENT AND A FUNGICIDE FROM THE GROUP CONSISTING OF INHIBITORS OF THE RESPIRATORY CHAIN AT COMPLEX I OR II BAYER CROPSCIENCE AG (DE) 2016-09-29 US claimed
WO-2009063075-A2 FUNGICIDAL MIXTURES II BASF SE (DE) 2009-05-22 WO claimed
WO-2009063076-A2 FUNGICIDAL MIXTURES III BASF SE (DE) 2009-05-22 WO claimed
WO-2009033582-A1 POST-HARVEST TREATMENT BAYER CROPSCIENCE AG (DE) 2009-03-19 WO claimed
EP-2036438-A1 Post-harvest treatment Bayer CropScience AG (DE) 2009-03-18 EP claimed
EP-2014166-A1 Active compound combinations Bayer CropScience AG (DE) 2009-01-14 EP claimed
WO-2008152092-A2 PESTICIDAL COMPOSITION COMPRISING A STRIGOLACTONE DERIVATIVE AND AN FUNGICIDE COMPOUND BAYER CROPSCIENCE SA (FR) 2008-12-18 WO claimed
WO-2008148859-A2 FUNGICIDAL MIXTURES BASF SE (DE) 2008-12-11 WO claimed
US-20080255107-A1 Fungicidal Mixtures Comprising N-[2-(Haloalk(Enyl)Oxy)Phenyl]Carboxamides BASF SE (DE) 2008-10-16 US claimed
WO-2008034785-A2 PESTICIDAL MIXTURES COMPRISING AN ANTHRANILAMIDE INSECTICIDE AND A FUNGICIDE BASF SE (DE) 2008-03-27 WO claimed
WO-2008034787-A2 PESTICIDAL MIXTURES COMPRISING AN ANTHRANILAMIDE INSECTICIDE AND A FUNGICIDE BASF SE (DE) 2008-03-27 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180103640-A1 PROCESS FOR IMPROVING SEEDLING GROWTH AND/OR EARLY EMERGENCE OF CROPS EEF1A1, BTF3, EEF1A2 LMNA 4223/4885POLB 2529/4885TSHR 3006/4885
US-20080255107-A1 Fungicidal Mixtures Comprising N-[2-(Haloalk(Enyl)Oxy)Phenyl]Carboxamides CBR3, CBR1, NAT1 LMNA 2193/4885POLB 3504/4885TSHR 2622/4885
US-20170265470-A1 Anthranilamides in combination with fungicides AADAC, ANTXR2, CYP51A1 LMNA 3681/4885POLB 4372/4885TSHR 4504/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.