SCHEMBL672497

SCHEMBL672497

Cn1cc(C(=O)Nc2ccccc2OC(F)(F)C(F)C(F)(F)F)c(C(F)(F)F)n1

nearest known ligand 0.53

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.53
POLB P06746 1/20 0.53
RECQL P46063 1/20 0.43
TSHR P16473 1/20 0.42
MAPK1 P28482 1/20 0.42
ATM Q13315 1/20 0.42
GAA P10253 2/20 0.41
DHODH Q02127 4/20 0.41
STING1 Q86WV6 1/20 0.40
IRAK4 Q9NWZ3 2/20 0.39
NTRK1 P04629 1/20 0.39
KMT2A Q03164 2/20 0.38
KDM4E B2RXH2 1/20 0.38
MEN1 O00255 1/20 0.38
ALDH1A1 P00352 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL69473 0.93 LMNA (0.53) LMNAPOLBTSHRMAPK1ATM
SCHEMBL29469563 0.93 LMNA (0.53) LMNAPOLBTSHRMAPK1ATM
SCHEMBL302641 0.90 LMNA (0.53) LMNAPOLBTSHRMAPK1ATM
SCHEMBL374012 0.88 RECQL (0.43) LMNAPOLBRECQLTSHRMAPK1
SCHEMBL29274932 0.87 LMNA (0.47) LMNAPOLBTSHRMAPK1ATM
SCHEMBL20560041 0.85 LMNA (0.52) LMNAPOLBATMGAADHODH
SCHEMBL4629736 0.85 RECQL (0.42) LMNAPOLBRECQLTSHRMAPK1
SCHEMBL3062126 0.84 TSHR (0.48) LMNAPOLBTSHRMAPK1ATM
SCHEMBL3672369 0.82 LMNA (0.46) LMNAPOLBTSHRMAPK1STING1
SCHEMBL3056538 0.82 LMNA (0.55) LMNAPOLBATMGAASTING1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 117 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112544622-B Preparation method of prevention and treatment agent for dragon fruit canker anthracnose 广西安农聚智科技有限公司 2021-07-02 CN claimed
CN-112544622-A Preparation method of prevention and treatment agent for dragon fruit canker anthracnose 广西安农聚智科技有限公司 2021-03-26 CN claimed
EP-2489262-B1 PESTICIDAL MIXTURES COMPRISING AN ANTHRANILAMIDE INSECTICIDE AND A FUNGICIDE BASF SE (DE) 2018-11-14 EP claimed
US-20150080215-A1 TERNARY PESTICIDAL MIXTURES BASF SE (DE) 2015-03-19 US claimed
US-20140179518-A1 Pesticidal Mixtures Comprising Cyanosulfoximine Compounds BASF SE (DE) 2014-06-26 US claimed
US-20130267414-A1 PESTICIDAL MIXTURES BASF SE (DE) 2013-10-10 US claimed
US-20130137571-A1 Crystalline Modification of Fipronil BASF SE (DE) 2013-05-30 US claimed
EP-2489264-A2 Pesticidal mixtures comprising an anthranilamide insecticide and a carboxamide fungicide BASF SE (DE) 2012-08-22 EP claimed
EP-2489262-A2 Pesticidal mixtures comprising an anthranilamide insecticide and a fungicide BASF SE (DE) 2012-08-22 EP claimed
EP-2489263-A2 Pesticidal mixtures comprising an anthranilamide insecticide and a fungicide BASF SE (DE) 2012-08-22 EP claimed
EP-2091330-A2 PESTICIDAL MIXTURES COMPRISING AN ANTHRANILAMIDE INSECTICIDE AND A FUNGICIDE BASF SE (DE) 2009-08-26 EP claimed
WO-2009062905-A1 PESTICIDAL MIXTURES COMPRISING CYANOSULFOXIMINE COMPOUNDS BASF SE (DE) 2009-05-22 WO claimed
WO-2009063075-A2 FUNGICIDAL MIXTURES II BASF SE (DE) 2009-05-22 WO claimed
WO-2009063076-A2 FUNGICIDAL MIXTURES III BASF SE (DE) 2009-05-22 WO claimed
WO-2009063074-A2 FUNGICIDAL MIXTURES I BASF SE (DE) 2009-05-22 WO claimed
WO-2008148859-A2 FUNGICIDAL MIXTURES BASF SE (DE) 2008-12-11 WO claimed
US-20080255107-A1 Fungicidal Mixtures Comprising N-[2-(Haloalk(Enyl)Oxy)Phenyl]Carboxamides BASF SE (DE) 2008-10-16 US claimed
WO-2008095913-A2 PESTICIDAL MIXTURES BASF SE (DE) 2008-08-14 WO claimed
WO-2008034787-A2 PESTICIDAL MIXTURES COMPRISING AN ANTHRANILAMIDE INSECTICIDE AND A FUNGICIDE BASF SE (DE) 2008-03-27 WO claimed
WO-2008034785-A2 PESTICIDAL MIXTURES COMPRISING AN ANTHRANILAMIDE INSECTICIDE AND A FUNGICIDE BASF SE (DE) 2008-03-27 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130267414-A1 PESTICIDAL MIXTURES AADAC, CTRL, AAAS LMNA 3546/4885POLB 4261/4885RECQL 1089/4885
US-20140179518-A1 Pesticidal Mixtures Comprising Cyanosulfoximine Compounds CPN1, SRM, STS LMNA 3355/4885POLB 3649/4885RECQL 318/4885
US-20080255107-A1 Fungicidal Mixtures Comprising N-[2-(Haloalk(Enyl)Oxy)Phenyl]Carboxamides CBR3, CBR1, NAT1 LMNA 2193/4885POLB 3504/4885RECQL 1908/4885
US-20130137571-A1 Crystalline Modification of Fipronil FIP1L1, PTMS, FIBP LMNA 2209/4885POLB 4375/4885RECQL 1801/4885
US-20150080215-A1 TERNARY PESTICIDAL MIXTURES AADAC, AS3MT, DDT LMNA 4360/4885POLB 4562/4885RECQL 2012/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.