Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 6/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | HTR2B | P41595 | 2/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1531218 | 0.98 | PTGS2 (0.42) | HTR2CPTGS2CHRNA7CA1CA2 | |
| SCHEMBL4286105 | 0.82 | PTGS2 (0.42) | HTR2CPTGS2HTR6 | |
| SCHEMBL20674413 | 0.81 | PTGES2 (0.43) | PTGS2CHRNA7CA1CA2 | |
| SCHEMBL3813336 | 0.81 | PTGS2 (0.36) | PTGS2CHRNA7CA1CA2 | |
| SCHEMBL29469849 | 0.77 | NOS3 (0.42) | HTR2CPTGS2CHRNA7CA1CA2 | |
| SCHEMBL4159762 | 0.75 | PTGES2 (0.44) | HTR2CPTGS2HTR6 | |
| SCHEMBL1954846 | 0.75 | CA1 (0.45) | CA1CA2 | |
| SCHEMBL28562885 | 0.75 | ACMSD (0.43) | PTGS2CA1CA2 | |
| SCHEMBL9627751 | 0.73 | HTR2C (0.46) | HTR2CPTGS2HTR2AHTR2B | |
| SCHEMBL20502275 | 0.72 | PKM (0.42) | HTR2CCA1CA2HTR2BHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4229048-A1 | SUBSTITUTED ACYL SULFONAMIDES FOR TREATING CANCER | The Broad Institute, Inc. (US) | 2023-08-23 | — | — | EP | disclosed |
| WO-2022081807-A1 | SUBSTITUTED ACYL SULFONAMIDES FOR TREATING CANCER | THE BROAD INSTITUTE, INC. (US) | 2022-04-21 | — | — | WO | disclosed |