SCHEMBL29470909

SCHEMBL29470909

CC(NC(=O)C(CCC(=O)O)NC(=O)C(N)CCCCN)C(=O)N1CCCC1C(=O)N1CCCC1C(=O)NC(C)C(=O)N1CCCC1C(=O)N1CCCC1C(=O)NC(CCC(N)=O)C(=O)NC(CO)C(=O)N1CCCC1C(=O)N1CCCC1C(N)=O

nearest known ligand 0.48

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ CAPN1 P07384 3/20 0.44
▸ GRB2 P62993 1/20 0.44
▸ OPRM1 P35372 1/20 0.42
▸ CXCL8 P10145 6/20 0.42
▸ TACR1 P25103 1/20 0.41
▸ BDKRB2 P30411 1/20 0.41
▸ NPY1R P25929 1/20 0.41
▸ NPY2R P49146 1/20 0.41
▸ NPY4R P50391 1/20 0.41
▸ NPY5R Q15761 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29471807 0.85 OPRM1 (0.51) CAPN1GRB2OPRM1TACR1BDKRB2
SCHEMBL29590494 0.84 OPRM1 (0.51) GRB2OPRM1BDKRB2
SCHEMBL30658587 0.84 F2 (0.46) GRB2OPRM1NPY1RNPY2RNPY4R
SCHEMBL29360886 0.84 GRB2 (0.49) CAPN1GRB2OPRM1CXCL8TACR1
SCHEMBL29630459 0.84 OPRM1 (0.53) OPRM1BDKRB2
SCHEMBL30844274 0.84 F2 (0.51) GRB2OPRM1TACR1
SCHEMBL30689897 0.83 CXCR4 (0.48) NPY1RNPY2RNPY4RNPY5R
SCHEMBL31126292 0.83 CAPN1 (0.43) CAPN1CXCL8
SCHEMBL31126285 0.83 BACE1 (0.43) CAPN1GRB2OPRM1
SCHEMBL29415462 0.83 F2 (0.47) GRB2OPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11795436-B2 Derivation of hepatic stem cells and mature liver cell types and uses thereof AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2023-10-24 — — US claimed
CN-108431209-B Derived and mature hepatocyte types of liver stem cells and uses thereof 新加坡科技研究局 2023-02-10 — — CN claimed
CN-114207111-B Method for producing skin-derived multipotent precursor cells 花王株式会社 2025-05-30 — — CN disclosed
CN-119968461-A Methods for differentiating endothelial cells 朗格生物技术公共公益股份有限公司 2025-05-09 — — CN disclosed
CN-119968458-A Methods for differentiating stromal cells or pericytes 朗格生物技术公共公益股份有限公司 2025-05-09 — — CN disclosed
WO-2025091318-A1 IMPROVED PRODUCTION OF INDUCED MIDBRAIN DOPAMINERGIC PROGENITOR CELLS FROM PLURIPOTENT STEM CELLS NUWACELL BIOTECHNOLOGIES CO., LTD. (CN) 2025-05-08 — — WO disclosed
CN-119948152-A Methods and compositions for inducing hematopoietic cell differentiation 菲特治疗公司 2025-05-06 — — CN disclosed
US-20250136934-A1 PRODUCTION OF INDUCED MIDBRAIN DOPAMINERGIC PROGENITOR CELLS FROM PLURIPOTENT STEM CELLS NUWACELL BIOTECHNOLOGIES CO., LTD. (CN) 2025-05-01 — — US disclosed
CN-119585417-A Methods for differentiating AT2 cells 朗格生物技术公共公益股份有限公司 2025-03-07 — — CN disclosed
CN-114164167-B Cell culture platform for single cell sorting and enhanced IPSC reprogramming 菲特治疗公司 2025-02-21 — — CN disclosed
CN-118871570-A Production of brown adipocytes from human pluripotent stem cells 布里格姆妇女医院 2024-10-29 — — CN disclosed
CN-118829724-A Method for inducing cell differentiation 科济生物医药(上海)有限公司 2024-10-22 — — CN disclosed
US-11795436-B2 Derivation of hepatic stem cells and mature liver cell types and uses thereof AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2023-10-24 — — US disclosed
CN-116121180-A Media and methods for producing cardiomyocytes from pluripotent stem cells 安徽中盛溯源生物科技有限公司 2023-05-16 — — CN disclosed
CN-108431209-B Derived and mature hepatocyte types of liver stem cells and uses thereof 新加坡科技研究局 2023-02-10 — — CN disclosed
US-11525133-B2 Chimeric proteins CAMBRIDGE ENTERPRISE LIMITED (GB) 2022-12-13 — — US disclosed
US-20220133740-A1 VALPROIC ACID COMPOUNDS AND WNT AGONISTS FOR TREATING EAR DISORDERS Frequency Therapeutics, Inc. (US) 2022-05-05 — — US disclosed
US-20220090054-A1 CHIMERIC PROTEINS CAMBRIDGE ENTERPRISE LIMITED (GB) 2022-03-24 — — US disclosed
US-11279925-B2 Chimeric proteins CAMBRIDGE ENTERPRISE LIMITED (GB) 2022-03-22 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220133740-A1 VALPROIC ACID COMPOUNDS AND WNT AGONISTS FOR TREATING EAR DISORDERS WNT3A, WNT1, WNT3 CAPN1 2517/4885GRB2 3638/4885OPRM1 3425/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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