Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.48 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.46 |
| ▸ | PPARG | P37231 | 7/20 | 0.46 |
| ▸ | PPARD | Q03181 | 7/20 | 0.46 |
| ▸ | PPARA | Q07869 | 7/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.46 |
| ▸ | TSHR | P16473 | 5/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TLR2 | O60603 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | FABP4 | P15090 | 2/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.46 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adipic Acid SCHEMBL5702263 | 0.84 | AKR1B1 (0.59) | AKR1B1GPR84PPARGPPARDPPARA | |
| Bicarbonate SCHEMBL4555786 | 0.84 | TSHR (0.38) | TSHRPTPN1MAPT | |
| Sebacic Acid SCHEMBL27799192 | 0.82 | GPR84 (0.61) | AKR1B1GPR84PPARGPPARDPPARA | |
| Adipic Acid SCHEMBL29895908 | 0.82 | AKR1B1 (0.62) | AKR1B1GPR84PPARGPPARDPPARA | |
| Adipic Acid SCHEMBL769185 | 0.82 | AKR1B1 (0.62) | AKR1B1GPR84PPARGPPARDPPARA | |
| Adipic Acid SCHEMBL28387530 | 0.80 | LMNA (0.52) | AKR1B1GPR84PPARGPPARDPPARA | |
| SCHEMBL29885317 | 0.80 | FFAR4 (0.52) | AKR1B1GPR84PPARGPPARDPPARA | |
| SCHEMBL3649789 | 0.80 | FFAR4 (0.52) | AKR1B1GPR84PPARGPPARDPPARA | |
| SCHEMBL18314429 | 0.80 | FFAR4 (0.52) | AKR1B1GPR84PPARGPPARDPPARA | |
| Sebacic Acid SCHEMBL2181971 | 0.80 | GPR84 (0.64) | AKR1B1GPR84PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114958285-B | Low-temperature activated single-component polyurethane sealant and preparation method thereof | 江门市聚晖新材料科技有限公司 | 2024-02-23 | — | — | CN | claimed |
| CN-114958285-A | Low-temperature activated single-component polyurethane sealant and preparation method thereof | 江门市聚晖新材料科技有限公司 | 2022-08-30 | — | — | CN | claimed |
| CN-110952335-B | Weather-resistant island-fixing fiber base cloth and preparation method and application thereof | 上海华峰超纤科技股份有限公司 | 2022-07-01 | — | — | CN | claimed |
| CN-110951024-A | Weather-resistant polyurethane resin and preparation method and application thereof | 上海华峰超纤材料股份有限公司 | 2020-04-03 | — | — | CN | claimed |
| CN-110952335-A | Weather-resistant island-fixing fiber base cloth and preparation method and application thereof | 上海华峰超纤材料股份有限公司 | 2020-04-03 | — | — | CN | claimed |
| JP-4318080-A | — | — | None | — | — | JP | disclosed |
| CN-118974190-A | Hot melt adhesive sheet | 日东新兴有限公司 | 2024-11-15 | — | — | CN | disclosed |
| CN-118946643-A | Hot melt adhesive sheet | 日东新兴有限公司 | 2024-11-12 | — | — | CN | disclosed |
| CN-117701135-A | Self-repairing polymer emulsion cement-based waterproof paint and preparation method thereof | 中冶武汉冶金建筑研究院有限公司 | 2024-03-15 | — | — | CN | disclosed |
| CN-114958285-B | Low-temperature activated single-component polyurethane sealant and preparation method thereof | 江门市聚晖新材料科技有限公司 | 2024-02-23 | — | — | CN | disclosed |
| CN-114698377-B | Polyurethane aqueous dispersion, inkjet ink composition, aqueous printing ink composition, and aqueous coating composition | 三洋化成工业株式会社 | 2024-01-30 | — | — | CN | disclosed |
| CN-112912248-B | Polyurethane resin aqueous dispersion, paint, film structure and structure | 大日精化工业株式会社 | 2023-06-13 | — | — | CN | disclosed |
| US-7759412-B2 | Tire puncture sealant | THE YOKOHAMA RUBBER CO., LTD. (JP) | 2010-07-20 | — | — | US | disclosed |
| US-20100152323-A1 | TIRE PUNCTURE SEALANT | THE YOKOHAMA RUBBER CO., LTD. (JP) | 2010-06-17 | — | — | US | disclosed |
| US-20100152322-A1 | TIRE PUNCTURE SEALANT | THE YOKOHAMA RUBBER CO., LTD. (JP) | 2010-06-17 | — | — | US | disclosed |
| US-20090312444-A1 | CAST MOLDED ARTICLE MADE OF POLYURETHANE POROUS SUBSTANCE AND METHOD FOR PRODUCING THE SAME | TOYO POLYMER CO., LTD. (JP) | 2009-12-17 | — | — | US | disclosed |
| US-20070203260-A1 | TIRE PUNCTURE SEALANT | THE YOKOHAMA RUBBER CO., LTD. (JP) | 2007-08-30 | — | — | US | disclosed |
| EP-1825991-A2 | Tire puncture sealant | THE YOKOHAMA RUBBER CO., LTD. (JP) | 2007-08-29 | — | — | EP | disclosed |
| US-6245695-B1 | BLEND OF CHLORINATED POLYOLEFIN FIRE RETARDANT AND A POLYESTERURETHANE COPOLYMER COMPRISING TRIMETHYL-1,6-HEXANEDIOL UNITS IN THE HIGH MOLECULAR WEIGHT POLYESTER BLOCK | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2001-06-12 | — | — | US | disclosed |
| JP-H04318080-A | INK COMPOSITION | DAINIPPON PRINTING CO LTD | 1992-11-09 | — | — | JP | disclosed |