Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.59 |
| ▸ | PPARG | P37231 | 7/20 | 0.59 |
| ▸ | PPARD | Q03181 | 7/20 | 0.59 |
| ▸ | PPARA | Q07869 | 7/20 | 0.59 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.59 |
| ▸ | TSHR | P16473 | 5/20 | 0.59 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | TLR2 | O60603 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | FABP4 | P15090 | 2/20 | 0.59 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.59 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.59 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.59 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | ESR1 | P03372 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adipic Acid SCHEMBL29895908 | 1.00 | AKR1B1 (0.62) | AKR1B1LMNAGPR84PPARGPPARD | |
| Sebacic Acid SCHEMBL2181971 | 0.97 | GPR84 (0.64) | AKR1B1LMNAGPR84PPARGPPARD | |
| Azelaic Acid SCHEMBL28166594 | 0.97 | GPR84 (0.64) | AKR1B1LMNAGPR84PPARGPPARD | |
| Glutarate SCHEMBL28037031 | 0.94 | SLC22A6 (0.61) | AKR1B1LMNAGPR84PPARGPPARD | |
| Hexanoate SCHEMBL25362962 | 0.93 | AKR1B1 (0.76) | AKR1B1LMNAGPR84PPARGPPARD | |
| Adipic Acid SCHEMBL11438883 | 0.93 | GPR84 (0.54) | AKR1B1LMNAGPR84PPARGPPARD | |
| Myristic Acid SCHEMBL769296 | 0.91 | GPR84 (0.77) | AKR1B1LMNAGPR84PPARGPPARD | |
| Dodecanoate SCHEMBL4241627 | 0.91 | GPR84 (0.77) | AKR1B1LMNAGPR84PPARGPPARD | |
| Stearic Acid SCHEMBL374745 | 0.91 | GPR84 (0.77) | AKR1B1LMNAGPR84PPARGPPARD | |
| SCHEMBL6746328 | 0.91 | FFAR4 (0.59) | AKR1B1LMNAGPR84PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 876 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110534239-A | A kind of ageing-resistant photovoltaic cable | ANHUI CABLE CO LTD | 2019-12-03 | — | — | CN | claimed |
| CN-110066525-A | A kind of environment protection architecture template | 李守征 | 2019-07-30 | — | — | CN | claimed |
| CN-109971252-A | A kind of UV ink-jet ink and preparation method thereof | 传美讯电子科技（珠海）有限公司 | 2019-07-05 | — | — | CN | claimed |
| CN-109834916-A | A kind of electric support Shooting Technique | 山东菏泽振华精密模具有限公司 | 2019-06-04 | — | — | CN | claimed |
| CN-107266884-B | A kind of 3D printing material of totally biodegradable and preparation method thereof | 吴新贤 | 2019-03-15 | — | — | CN | claimed |
| CN-109422925-A | A kind of anti-oilcloth of PVC coating | 于银强 | 2019-03-05 | — | — | CN | claimed |
| CN-109337172-A | A kind of enhanced plastic bucket | 江门市恒荣塑料制品有限公司 | 2019-02-15 | — | — | CN | claimed |
| CN-106192443-B | A kind of anion ecological artificial leather and preparation method thereof | 南通中豪超纤制品有限公司 | 2019-02-01 | — | — | CN | claimed |
| CN-109233072-A | A kind of PE plastic barrel | 江门市恒荣塑料制品有限公司 | 2019-01-18 | — | — | CN | claimed |
| CN-109112846-A | A kind of high-strength abrasion-proof plated film PVC artificial leather | 南通中奥车用新材料有限公司 | 2019-01-01 | — | — | CN | claimed |
| EP-1991515-A2 | BIO-DERIVED 1,3-PROPANEDIOL AND ITS CONJUGATE ESTERS AS NATURAL AND NON IRRITATING SOLVENTS FOR BIOMASS-DERIVED EXTRACTS FRAGRANCE CONCENTRATES, AND OILS | DuPont Tate & Lyle Bio Products Company, LLC (US) | 2008-11-19 | — | — | EP | claimed |
| WO-2008123845-A2 | COMPOSITIONS COMPRISING MONO AND DI ESTERS OF BIOLOGICALLY-BASED 1.3-PROPANEDIOL | DUPONT TATE & LYLE BIO PRODUCTS COMPANY, LLC (US) | 2008-10-16 | — | — | WO | claimed |
| US-20070213247-A1 | Detergent and liquid soap compositions comprising biologically-based mono and di esters | DUPONT TATE & LYLE BIO PRODUCTS COMPANY, LLC | 2007-09-13 | — | — | US | claimed |
| US-20070207939-A1 | Compositions comprising mono and di esters of biologically-based 1,3-propanediol | DUPONT TATE & LYLE BIO PRODUCTS COMPANY, LLC | 2007-09-06 | — | — | US | claimed |
| US-20070202126-A1 | biodegradable; improved anthropogenic carbon dioxide emission profile | BARCLAYS BANK PLC, AS COLLATERAL AGENT | 2007-08-30 | — | — | US | claimed |
| US-20070202580-A1 | Synthesis of mono and di esters from biologically-produced 1,3-propanediol | BARCLAYS BANK PLC, AS COLLATERAL AGENT | 2007-08-30 | — | — | US | claimed |
| US-20070203276-A1 | Plasticizers comprising biologically-based mono and di esters | DUPONT TATE & LYLE BIO PRODUCTS COMPANY, LLC | 2007-08-30 | — | — | US | claimed |
| US-20070202073-A1 | Personal care and cosmetics compositions comprising biologically-based mono and di esters | DUPONT TATE &LYLE BIO PRODUCTS COMPANY, LLC | 2007-08-30 | — | — | US | claimed |
| US-20070203323-A1 | Food compositions comprising biologically-based biodegradable 1,3-propanediol esters | DUPONT TATE & LYLE BIO PRODUCTS COMPANY, LLC | 2007-08-30 | — | — | US | claimed |
| WO-2007095262-A2 | BIO-DERIVED 1,3-PROPANEDIOL AND ITS CONJUGATE ESTERS AS NATURAL AND NON IRRITATING SOLVENTS | DUPONT TATE & LYLE BIO PRODUCTS COMPANY, LLC (US) | 2007-08-23 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070202580-A1 | Synthesis of mono and di esters from biologically-produced 1,3-propanediol | DECR1, DECR2, HSD17B12 | AKR1B1 203/4885LMNA 3804/4885GPR84 1943/4885 |
| US-20070202126-A1 | biodegradable; improved anthropogenic carbon dioxide emission profile | BMP2, PGD, EBP | AKR1B1 1405/4885LMNA 1877/4885GPR84 3746/4885 |
| US-20070202073-A1 | Personal care and cosmetics compositions comprising biologically-based mono and di esters | PBDC1, CUTA, EBP | AKR1B1 167/4885LMNA 1332/4885GPR84 2433/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.