Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | VCP | P55072 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.46 |
| ▸ | CTRC | Q99895 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3562751 | 0.91 | KDM4E (0.53) | KDM4EALDH1A1HSD17B10ALOX5HPGD | |
| SCHEMBL3565117 | 0.88 | KDM4E (0.50) | KDM4EALDH1A1HSD17B10ALOX5HPGD | |
| SCHEMBL3559622 | 0.88 | KDM4E (0.50) | KDM4EALDH1A1HSD17B10ALOX5HPGD | |
| SCHEMBL3564375 | 0.84 | ALDH1A1 (0.48) | KDM4EALDH1A1HSD17B10ALOX5HPGD | |
| SCHEMBL3572101 | 0.82 | MCL1 (0.58) | KDM4EALDH1A1HSD17B10ALOX5HPGD | |
| SCHEMBL29473456 | 0.82 | KDM4E (0.56) | KDM4EALDH1A1HSD17B10TP53GAA | |
| SCHEMBL4659182 | 0.81 | ALOX5 (0.44) | KDM4EALDH1A1HSD17B10ALOX5HPGD | |
| SCHEMBL2848055 | 0.81 | RAD51 (0.48) | KDM4EALDH1A1HSD17B10ALOX5HPGD | |
| SCHEMBL28726697 | 0.80 | SDHB (0.51) | KDM4EALDH1A1HPGDTP53MAPT | |
| SCHEMBL28726706 | 0.79 | NOS3 (0.47) | KDM4EALDH1A1HSD17B10ALOX5HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110156668-B | Method for synthesizing 4-polyfluoroalkyl-2, 6-diaryl substituted pyridine compound | 福州大学 | 2022-04-26 | — | — | CN | disclosed |