Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | NPC1 | O15118 | 4/20 | 0.59 |
| ▸ | RAB9A | P51151 | 4/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | STAT3 | P40763 | 1/20 | 0.59 |
| ▸ | STAT1 | P42224 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | NLRP3 | Q96P20 | 5/20 | 0.51 |
| ▸ | MMP1 | P03956 | 3/20 | 0.50 |
| ▸ | MMP2 | P08253 | 3/20 | 0.50 |
| ▸ | MMP9 | P14780 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29473480 | 0.92 | ALDH1A1 (0.70) | ALDH1A1CYP1A2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7097165 | 0.85 | ALDH1A1 (0.67) | ALDH1A1CYP1A2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL216958 | 0.81 | TDP1 (0.70) | ALDH1A1CYP1A2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9867574 | 0.81 | ALDH1A1 (0.62) | ALDH1A1CYP1A2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28724485 | 0.81 | KMT2A (0.61) | ALDH1A1CYP1A2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29473463 | 0.81 | KMT2A (0.61) | ALDH1A1CYP1A2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL18685510 | 0.81 | ALDH1A1 (0.53) | ALDH1A1CYP1A2NPC1RAB9ASMN1; SMN2 | |
| Metacetamol SCHEMBL31195432 | 0.80 | ALDH1A1 (1.00) | ALDH1A1CYP1A2NPC1RAB9ASMN1; SMN2 | |
| Metacetamol SCHEMBL181254 | 0.80 | ALDH1A1 (1.00) | ALDH1A1CYP1A2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9400341 | 0.79 | ALDH1A1 (0.70) | ALDH1A1CYP1A2NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117986220-A | Method for preparing substituted chromanone derivative | 杭州杜易科技有限公司 | 2024-05-07 | — | — | CN | disclosed |
| CN-114222734-A | Method for preparing substituted chromanone derivative | 杭州杜易科技有限公司 | 2022-03-22 | — | — | CN | disclosed |